NOAEL Data Cosmetic Ingredient

Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy-

Also known as: Benzeneacetic acid, α,4-dihydroxy-3-methoxy-, Mandelic acid, 4-hydroxy-3-methoxy-, α,4-Dihydroxy-3-methoxybenzeneacetic acid, Vanillomandelic acid, Vanilmandelic acid (+14 more)

CAS 55-10-7

Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy- (CAS 55-10-7) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Vanillylmandelic Acid →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 25 fields

Name

Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy-

CAS Number

55-10-7

DTXSID

DTXSID10861583

Molecular Formula

C9H10O5

InChI Key

CGQCWMIAEPEHNQ-UHFFFAOYSA-N

Monoisotopic Mass

198.052823

Synonyms

Benzeneacetic acid, α,4-dihydroxy-3-methoxy-Mandelic acid, 4-hydroxy-3-methoxy-α,4-Dihydroxy-3-methoxybenzeneacetic acidVanillomandelic acidVanilmandelic acidVanillinmandelic acid4′-Hydroxy-3′-methoxymandelic acidDL-Vanillylmandelic acid4-Hydroxy-3-methoxy-DL-mandelic acidDL-Vanillomandelic acidVanillyl-dl-mandelic acid(4-Hydroxy-3-methoxyphenyl)glycolic acid

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records

Flavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records

List	Keyword	Source
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)	FDA	United States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies

Value	Unit	Endpoint	Route	Species	Source
0DQI268449	UNII	FDA UNII substance identifier	-	-	openFDA substances
0DQI268449	UNII	FDA UNII substance identifier	-	-	openFDA substances
0DQI268449	UNII	FDA UNII substance identifier	-	-	openFDA substances
0DQI268449	UNII	FDA UNII substance identifier	-	-	openFDA substances

Showing 4 of 4 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL1256396

ChEMBL Phase

Not listed

Adverse Events

Bioactivity

View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy-?

Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy- has 4 NOAEL studies in the database. The lowest reported value is 0DQI268449 UNII. Source: openFDA substances.

What regulatory lists include Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy-?

Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy- appears on 1 regulatory/inventory list including food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.

Is Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy- used in cosmetics?

Yes, Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy- is also indexed as a cosmetic ingredient under the name Vanillylmandelic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy- come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy- used outside industrial chemicals?

Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy- also appears in cosmetics, pharmaceutical, food safety, cannabis databases.