What is the NOAEL for Hydroxylamine hydrochloride?
Hydroxylamine hydrochloride has 5 NOAEL studies in the database. The lowest reported value is 0.02 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Hydroxylamine hydrochloride
Also known as: Hydroxylamine, hydrochloride, Hydroxylamine, hydrochloride (1:1), Hydroxylamine HCl, EINECS 226-798-2, Hydroxylamine chloride (1:1) (+2 more)
CAS 5470-11-1
Hydroxylamine hydrochloride (CAS 5470-11-1) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Cross-Vertical Regulatory Divergence
Hydroxylamine hydrochloride is prohibited in EU cosmetics but has active industrial GHS classifications (H290, H302, H312, H315, H317, H319, H351, H373).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
NOAEL studies
NOAEL studies
5
SOURCE
Chemical inventory jurisdictions
Regulatory lists
2
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Hydroxylamine hydrochloride
CAS Number
5470-11-1
DTXSID
DTXSID7025425
Molecular Formula
ClH.H4NO
InChI Key
WCYJQVALWQMJGE-UHFFFAOYSA-M
Monoisotopic Mass
70.005966
Synonyms
Hydroxylamine, hydrochlorideHydroxylamine, hydrochloride (1:1)Hydroxylamine HClEINECS 226-798-2Hydroxylamine chloride (1:1)Hydroxylamine-1-hydrochlorideUNII-5X4ZA62Z4Q
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
WHO/JECFA
1 records
| Field | Value |
|---|---|
| GHS Signal Word | DANGER |
| GHS Hazard Statements | May be osive to metals Toxic if swallowed Harmful in contact with skin Causes skin and eye irritation May cause an allergic skin reaction Suspected of causing cancer May cause damage to blood May cause damage to blood through prolonged or repeated exposure Very toxic to aquatic life |
| Short-term Effects | The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. Medical observation is indicated. |
| Long-term Effects | Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the blood. This may result in the formation of methaemoglobin. Tumours have been detected in experimental animals but may not be relevant to humans. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Antioxidant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| fracking; water | NY Department of Conservation | CPCat |
| banned; Europe; Personal care | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.02 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| 5X4ZA62Z4Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5X4ZA62Z4Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5X4ZA62Z4Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5X4ZA62Z4Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Hydroxylammonium chloride | 226-798-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
HYDROXYLAMMONIUM CHLORIDE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Frequently Asked Questions
What regulatory lists include Hydroxylamine hydrochloride?
Hydroxylamine hydrochloride appears on 2 regulatory/inventory lists including fracking; water, banned; Europe; Personal care. Source: EPA CPDat.
Is Hydroxylamine hydrochloride used in cosmetics?
Yes, Hydroxylamine hydrochloride is also indexed as a cosmetic ingredient under the name Hydroxylamine HCl. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Hydroxylamine hydrochloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Hydroxylamine hydrochloride have different safety status in cosmetics vs industrial chemicals?
Hydroxylamine hydrochloride is prohibited in EU cosmetics but has active industrial GHS classifications (H290, H302, H312, H315, H317, H319, H351, H373).
Is Hydroxylamine hydrochloride used outside industrial chemicals?
Hydroxylamine hydrochloride also appears in cosmetics, pharmaceutical databases.