What is the NOAEL for Tricaprylin?
Tricaprylin has 10 NOAEL studies in the database. The lowest reported value is 6P92858988 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Tricaprylin
Also known as: Octanoic acid triglyceride, Octanoic acid, 1,2,3-propanetriyl ester, Glycerin tricaprylate, Trioctanoin, 4-02-00-00991 (+14 more)
CAS 538-23-8
Tricaprylin (CAS 538-23-8) is a chemical substance. Key regulatory status: REACH registered, 14 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
10
SOURCE
chemical inventory jurisdictions
Regulatory lists
14
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
Tricaprylin
CAS Number
538-23-8
DTXSID
DTXSID6021375
Molecular Formula
C27H50O6
InChI Key
VLPFTAMPNXLGLX-UHFFFAOYSA-N
Monoisotopic Mass
470.360739
Synonyms
Octanoic acid triglycerideOctanoic acid, 1,2,3-propanetriyl esterGlycerin tricaprylateTrioctanoin4-02-00-00991BRN 1717202EINECS 208-686-5MaceightPanacete 800Trioctanoin oilUNII-6P928589881,2,3-Propanetriol trioctanoate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
17 records
DeodorizerSoftener and conditionerFragranceSolventHumectant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
14 records
| List | Keyword | Source |
|---|---|---|
| consumer_product | P&G | Proctor & Gamble |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| artificial_saliva; detected; emissions; Europe; Furniture and Furnishings | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - general moisturizing - hand/body lotion | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 6P92858988 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6P92858988 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6P92858988 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6P92858988 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =33300 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =34200 | mg/kg bw | LD50 | oral | Rat (Male) | NTP_ICE_acute_oral |
| =4770 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =9540 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =1908 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =4770 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 10 of 10 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Glycerol trioctanoate | 208-686-5 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
TRICAPRILIN
ChEMBL Phase
3
Adverse Events
0
Bioactivity
3
Frequently Asked Questions
What regulatory lists include Tricaprylin?
Tricaprylin appears on 9 regulatory/inventory lists including consumer_product, detected; Europe; Other direct contact consumer goods, air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe, and 6 more. Source: EPA CPDat.
Is Tricaprylin used in cosmetics?
Yes, Tricaprylin is also indexed as a cosmetic ingredient under the name Tricaprylin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Tricaprylin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Tricaprylin used outside industrial chemicals?
Tricaprylin also appears in cosmetics, pharmaceutical databases.