What is the NOAEL for Butanoic acid, 3-hydroxy-, butyl ester?
Butanoic acid, 3-hydroxy-, butyl ester has 2 NOAEL studies in the database. The lowest reported value is 2.94 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Butanoic acid, 3-hydroxy-, butyl ester
CAS 53605-94-0
Butanoic acid, 3-hydroxy-, butyl ester (CAS 53605-94-0) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
Cross-Vertical Regulatory Divergence
Butanoic acid, 3-hydroxy-, butyl ester is prohibited in EU cosmetics but has active industrial GHS classifications (H319).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
2
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
Butanoic acid, 3-hydroxy-, butyl ester
CAS Number
53605-94-0
DTXSID
DTXSID20886065
Molecular Formula
C8H16O3
InChI Key
LHDWRKCOQQHAMP-UHFFFAOYSA-N
Monoisotopic Mass
160.109944
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
SolventCleaning agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 2 of 2 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =2.94 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 2 of 2 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Butyl 3-hydroxybutyrate | 258-658-1 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Solvent
Frequently Asked Questions
What regulatory lists include Butanoic acid, 3-hydroxy-, butyl ester?
Butanoic acid, 3-hydroxy-, butyl ester appears on 1 regulatory/inventory list including SCIL (9/2019). Source: EPA CPDat.
Is Butanoic acid, 3-hydroxy-, butyl ester used in cosmetics?
Yes, Butanoic acid, 3-hydroxy-, butyl ester is also indexed as a cosmetic ingredient under the name Butyl Hydroxybutyrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Butanoic acid, 3-hydroxy-, butyl ester come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Butanoic acid, 3-hydroxy-, butyl ester have different safety status in cosmetics vs industrial chemicals?
Butanoic acid, 3-hydroxy-, butyl ester is prohibited in EU cosmetics but has active industrial GHS classifications (H319).
Is Butanoic acid, 3-hydroxy-, butyl ester used outside industrial chemicals?
Butanoic acid, 3-hydroxy-, butyl ester also appears in cosmetics databases.