What is the NOAEL for Sodium benzoate?
Sodium benzoate has 80 NOAEL studies in the database. The lowest reported value is 0 unitless. Source: NTP_ICE_endocrine.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Sodium benzoate
Also known as: Benzoic acid, sodium salt, Benzoate, sodium, Benzoate sodium, Caswell No. 746, EINECS 208-534-8 (+8 more)
CAS 532-32-1
Sodium benzoate (CAS 532-32-1) is a chemical substance. Key regulatory status: REACH registered, 30 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
View cosmetic safety profile for Ingredient compliance data extraction →
SOURCE
noael studies public
NOAEL studies
80
SOURCE
chemical inventory jurisdictions
Regulatory lists
30
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
Sodium benzoate
CAS Number
532-32-1
DTXSID
DTXSID1020140
Molecular Formula
C7H6O2.Na
InChI Key
WXMKPNITSTVMEF-UHFFFAOYSA-M
Synonyms
Benzoic acid, sodium saltBenzoate, sodiumBenzoate sodiumCaswell No. 746EINECS 208-534-8EPA Pesticide Chemical Code 009103FEMA No. 3025FEMA Number 3025Natrium benzoicumBenzoan sodnyBenzoesaeure (na-salz)UNII-OJ245FE5EU
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | The substance is mildly irritating to the eyes. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
PreservativeCorrosion inhibitorBiocideDeodorizerNo specific technical functionFragranceCrystal growth modifiers (nucleating agents)PharmaceuticalFood preservativeProcessing aids not otherwise specifiedpH regulating agentStabilizing agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
30 records
| List | Keyword | Source |
|---|---|---|
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Europe; Personal care - body hygiene - hand soap | Danish Environmental Protection Agency | Danish EPA |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| detected; general_crops; Pesticides; residue | FDA | United States Food and Drug Administration (FDA) |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - body hygiene - body wash | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - hair styling and care - shampoo | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - specialized bath products - bubble bath | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - dental care - toothpaste | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - hair styling and care - shampoo-dandruff | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - liniment | Danish Environmental Protection Agency | Danish EPA |
| Australia; Food and drug - smoking-related products | New Zealand ESR | CPCat |
| Europe; plastic_additive | European Chemicals Agency | European Chemicals Agency (ECHA) |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Cleaning products and household care - dishwasher and dishes - automatic dishwashing detergent; Europe | Danish EPA | Danish EPA |
| fracking; water | NY Department of Conservation | CPCat |
| Europe; Personal care - oral and dental care - teeth whitener | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 50 of 80 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| range:0-0.50.5 | mg/kg bw/day | ADI | - | Rat | INCHEM_WHO_jecfa_jecmono_v1037je01 |
| range:0-0.50.5 | mg/kg bw/day | ADI | - | Rat | INCHEM_WHO_jecfa_jecmono_v83je01 |
| range:0-0.50.5 | mg/kg bw/day | ADI | - | Rat | INCHEM_WHO_jecfa_jecmono_v1037je01 |
| range:0-0.50.5 | mg/kg bw/day | ADI | - | Rat | INCHEM_WHO_jecfa_jecmono_v83je01 |
| range:0-55 | mg/kg bw/day | ADI | - | - | INCHEM_WHO_jecfa_jecmono_v1037je01 |
| range:0-55 | mg/kg bw/day | ADI | - | - | INCHEM_WHO_jecfa_jecmono_v83je01 |
| range:0-55 | mg/kg bw/day | ADI | - | - | INCHEM_WHO_jecfa_jecmono_v1037je01 |
| range:0-55 | mg/kg bw/day | ADI | - | - | INCHEM_WHO_jecfa_jecmono_v83je01 |
| range:0-2020 | mg/kg bw/day | ADI | - | - | INCHEM_WHO_jecfa_jecmono_v1037je01 |
| range:0-2020 | mg/kg bw/day | ADI | - | - | INCHEM_WHO_jecfa_jecmono_v83je01 |
| range:0-2020 | mg/kg bw/day | ADI | - | - | INCHEM_WHO_jecfa_jecmono_v1037je01 |
| range:0-2020 | mg/kg bw/day | ADI | - | - | INCHEM_WHO_jecfa_jecmono_v83je01 |
| =5 | mg/kg bw/day | ADI (group) | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =5 | mg/kg bw/day | ADI (group) | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =0.1 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =3 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| OJ245FE5EU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OJ245FE5EU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OJ245FE5EU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OJ245FE5EU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =4070 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =36000 | mg/kg bw/day | LEL | oral | Pig | ToxValDB_EFSA |
| 6290 | mg/kg bw/day | LOAEL | oral | rat | COSMOS_DB |
| =2002 | mg/kg bw/day | LOEL | oral | Rat | ToxValDB_ECOTOX |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =3.6 | mg/kg bw/day | NOAEL | oral | - | INCHEM_WHO_jecfa_jecmono_v1037je01 |
| =3.6 | mg/kg bw/day | NOAEL | oral | - | INCHEM_WHO_jecfa_jecmono_v83je01 |
| =3.6 | mg/kg bw/day | NOAEL | oral | - | INCHEM_WHO_jecfa_jecmono_v1037je01 |
| =3.6 | mg/kg bw/day | NOAEL | oral | - | INCHEM_WHO_jecfa_jecmono_v83je01 |
| 175 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| =190 | mg/kg bw/day | NOAEL | - | - | INCHEM_WHO_jecfa_jecmono_v83je01 |
| =190 | mg/kg bw/day | NOAEL | - | - | INCHEM_WHO_jecfa_jecmono_v83je01 |
| =200 | mg/kg bw/day | NOAEL | - | - | INCHEM_WHO_jecfa_jecmono_v1037je01 |
| =200 | mg/kg bw/day | NOAEL | - | - | INCHEM_WHO_jecfa_jecmono_v83je01 |
| =200 | mg/kg bw/day | NOAEL | - | - | INCHEM_WHO_jecfa_jecmono_v1037je01 |
| =200 | mg/kg bw/day | NOAEL | - | - | INCHEM_WHO_jecfa_jecmono_v83je01 |
| 250 | mg/kg bw/day | NOAEL | oral | rabbit | COSMOS_DB |
| =250 | mg/kg bw/day | NOAEL | oral | Rabbit | ToxValDB_ECHA_IUCLID |
| 300 | mg/kg bw/day | NOAEL | oral | hamster | COSMOS_DB |
| =410 | mg/kg bw/day | NOAEL | - | - | INCHEM_WHO_jecfa_jecmono_v83je01 |
| =410 | mg/kg bw/day | NOAEL | - | - | INCHEM_WHO_jecfa_jecmono_v83je01 |
| =500 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =500 | mg/kg bw/day | NOAEL | oral | Rat; Bird | INCHEM_WHO_jecfa_jecmono_v83je01 |
| =500 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =500 | mg/kg bw/day | NOAEL | oral | Rat; Bird | INCHEM_WHO_jecfa_jecmono_v83je01 |
| 510 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =905 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 1000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =1000 | mg/kg bw/day | NOAEL | - | - | INCHEM_WHO_jecfa_jecmono_v1037je01 |
Showing 50 of 80 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Sodium benzoate | 208-534-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Other
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
SODIUM BENZOATE
ChEMBL Phase
4
Adverse Events
147
Bioactivity
4
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Sodium benzoate?
Sodium benzoate appears on 22 regulatory/inventory lists including SCIL (9/2019), Canada; consumer_product; Substances in Products - Canada (4/2014), inert_ingredient; Pesticides, and 19 more. Source: EPA CPDat.
Is Sodium benzoate used in cosmetics?
Yes, Sodium benzoate is also indexed as a cosmetic ingredient under the name Ingredient compliance data extraction. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium benzoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Sodium benzoate used outside industrial chemicals?
Sodium benzoate also appears in cosmetics, pharmaceutical, cannabis databases.