Also known as: Deltamethrin [BSI:ISO], (S)-alpha-Cyano-3-phenoxybenzyl (1R,3R)-3-(2,2-dibromovinyl)-2,2-dimethyl-cyclopropan-1-carboxylate, (S)-alpha-Cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate, (S)-alpha-Cyano-3-phenoxybenzyl-(1R)-cis-3-(2,2-dibromovinyl)-2,2-dimethyl-cyclopropane carboxyate, (1R-(1alpha(S*),3alpha))-Cyano(3-phenoxyphenyl)methyl 3-(2,2-dibromoethenyl)-2,2-dimethylcyclopropanecarboxylate (+9 more)
CAS 52918-63-5
Deltamethrin (CAS 52918-63-5) is a chemical substance with GHS signal word Danger; key hazard signal: H331; H301; H400; H410. Key regulatory status: 60 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, IARC, ILO ICSC.
Deltamethrin is prohibited in EU cosmetics but has active industrial GHS classifications (H331, H301, H400, H410).
CAS, identifiers, formula, and alternate names for the matched substance record.
Carcinogenic hazard classification from IARC monograph evaluations.
| Group | Meaning | Evaluated | Volume |
|---|---|---|---|
| Group 3 | Not classifiable | 1990 | 53 |
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Acute Tox. 3 *; Acute Tox. 3 *; Aquatic Acute 1; Aquatic Chronic 1 | H331; H301; H400; H410 | GHS06; GHS09 | Danger |
International Chemical Safety Card hazard and exposure summary.
| Field | Value |
|---|---|
| GHS Signal Word | DANGER |
| GHS Hazard Statements | Toxic if swallowed or if inhaled Causes mild skin irritation Causes eye irritation Causes damage to central nervous system May cause respiratory irritation Very toxic to aquatic life with long lasting effects |
| Short-term Effects | The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the nervous system. The effects may be delayed. Exposure through the skin could cause local effects, including sensations such as tingling, itching or burning. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation and by ingestion. |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| active_ingredient; agricultural; applied; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; grain; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| agricultural; detected; fruits_and_vegetables; Pesticides; residue | USDA | United States Department of Agriculture (USDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
| active_ingredient; agricultural; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; applied; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; applied; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; Australia | Australian Pesticides and Veterinary Medicines Authority | CPCat |
| active_ingredient; agricultural; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| <=0.01 | mg/kg | ADI | oral | Human | ToxValDB_WHO_JECFA_ADI |
| =0.01 | mg/kg bw/day | ADI | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =0.01 | mg/kg bw/day | ADI | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =0.01 | mg/kg bw | ARfD | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =0.01 | mg/kg bw | ARfD | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| 7 | uL/min/10^6 cells | Clint | - | Rat | NTP_ICE_adme_parameters |
| 1 | unitless | EPA Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 3 | unitless | EPA Classification | Inhalation | - | NTP_ICE_acute_inhalation |
| 3 | unitless | EPA Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 4 | unitless | EPA Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| =2 | Unitless | EPA classification | oral | Rat (Male) | NTP_ICE_acute_oral |
| =2 | Unitless | EPA classification | oral | Rat (Female) | NTP_ICE_acute_oral |
| 2 | unitless | EPA classification | Dermal | Rabbit | NTP_ICE_skin_irritation |
| 3 | unitless | EPA classification | Dermal | Rat | NTP_ICE_acute_dermal |
| =3 | Unitless | EPA classification | oral | Rat (Female) | NTP_ICE_acute_oral |
| 3 | unitless | EPA classification | Dermal | Rabbit | NTP_ICE_skin_irritation |
| 4 | unitless | EPA classification | Dermal | Rat | NTP_ICE_acute_dermal |
| =4 | Unitless | EPA classification | oral | Rat (Female) | NTP_ICE_acute_oral |
| 4 | unitless | EPA classification | Dermal | Rabbit | NTP_ICE_skin_irritation |
| 2JTS8R821G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2JTS8R821G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2JTS8R821G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2JTS8R821G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.01 | fraction | Fu | - | Human | NTP_ICE_adme_parameters |
| 0.049 | fraction | Fu | - | Rat | NTP_ICE_adme_parameters |
| 1 | unitless | GHS Classification | Dermal | Guinea pig | NTP_ICE_skin_sensitization |
| 4 | unitless | GHS Classification | Inhalation | - | NTP_ICE_acute_inhalation |
| =3 | Unitless | GHS classification | oral | Rat (Female) | NTP_ICE_acute_oral |
| =3 | Unitless | GHS classification | oral | Rat (Female) | NTP_ICE_acute_oral |
| =4 | Unitless | GHS classification | oral | Rat (Female) | NTP_ICE_acute_oral |
| =4 | Unitless | GHS classification | oral | Rat (Male) | NTP_ICE_acute_oral |
| 5 | unitless | GHS classification | Dermal | Rat | NTP_ICE_acute_dermal |
| =5 | Unitless | GHS classification | oral | Rat (Female) | NTP_ICE_acute_oral |
| 3 | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 3 | unitless | IARC group | - | - | NTP_ICE_cancer |
| 5840 | nM | IC25 | - | - | NTP_ICE_endocrine |
| range0.53 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| 0.7 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| 0.785 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| >2.04 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| 4.35 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| =150 | mg/kg bw | LD50 | oral | Rat (Female) | NTP_ICE_acute_oral |
| =196 | mg/kg bw | LD50 | oral | Rat (Female) | NTP_ICE_acute_oral |
| =249 | mg/kg bw | LD50 | oral | Rat (Male/Female) | NTP_ICE_acute_oral |
| =322 | mg/kg bw | LD50 | oral | Rat (Male) | NTP_ICE_acute_oral |
| =1750 | mg/kg bw | LD50 | oral | Rat (Female) | NTP_ICE_acute_oral |
| >2000 | mg/kg | LD50 | Dermal | Rat | NTP_ICE_acute_dermal |
| >5000 | mg/kg | LD50 | Dermal | Rat | NTP_ICE_acute_dermal |
| >5000 | mg/kg bw | LD50 | oral | Rat (Male) | NTP_ICE_acute_oral |
| >1.134 | mg/kg bw/day | LEL | oral | Dog | ToxValDB_ToxRefDB |
Showing 50 of 100 studies
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Same-CAS cannabis compliance and lab records where available.
1 cannabis record found in efsa substances.
View full cannabis profile →Deltamethrin (CAS 52918-63-5) is classified under EU CLP Annex VI as Acute Tox. 3 *; Acute Tox. 3 *; Aquatic Acute 1; Aquatic Chronic 1 with signal word Danger. Hazard statements: H331; H301; H400; H410. Source: EU CLP Annex VI (ECHA).
Deltamethrin has 100 NOAEL studies in the database. The lowest reported value is 0.005 ml/kg via dermal in Rat. Source: ToxValDB_ECOTOX.
Deltamethrin appears on 8 regulatory/inventory lists including active_ingredient; agricultural; applied; Pesticides, active_ingredient; Europe; Pesticides, agricultural; detected; fruits_and_vegetables; Pesticides; residue, and 5 more. Source: EPA CPDat.
Deltamethrin is classified by IARC as Group 3 — not classifiable as to its carcinogenicity to humans (evaluated 1990). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.
Yes, Deltamethrin is also indexed as a cosmetic ingredient under the name Deltamethrin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, EPA DSSTox, IARC Monographs, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Deltamethrin is prohibited in EU cosmetics but has active industrial GHS classifications (H331, H301, H400, H410).
Deltamethrin also appears in cosmetics, pharmaceutical, cannabis databases.