What is the NOAEL for Sodium D-gluconate?
Sodium D-gluconate has 7 NOAEL studies in the database. The lowest reported value is R6Q3791S76 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Sodium D-gluconate
Also known as: D-Gluconic acid, monosodium salt, EINECS 208-407-7, Gluconato di sodio, UNII-R6Q3791S76, Monosodium D-gluconate (+1 more)
CAS 527-07-1
Sodium D-gluconate (CAS 527-07-1) is a chemical substance. Key regulatory status: 13 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ILO ICSC.
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
13
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
Sodium D-gluconate
CAS Number
527-07-1
DTXSID
DTXSID7027170
Molecular Formula
C6H12O7.Na
InChI Key
UPMFZISCCZSDND-JJKGCWMISA-M
Synonyms
D-Gluconic acid, monosodium saltEINECS 208-407-7Gluconato di sodioUNII-R6Q3791S76Monosodium D-gluconatesodium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| GHS Hazard Statements | No hazard classification according to GHS criteria |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Chelating agentSoftener and conditionerCleaning agentDyepH regulating agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
13 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Europe; supplements | EU | CPCat |
| Europe; food_additive; supplements | EU | CPCat |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| animal_products | USDA | United States Department of Agriculture (USDA) |
| animal_products | USDA | United States Department of Agriculture (USDA) |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| R6Q3791S76 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R6Q3791S76 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R6Q3791S76 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R6Q3791S76 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =5 | % | NOAEL | oral | Rat | ToxValDB_HESS |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HESS |
| =4100 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HESS |
Showing 7 of 7 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
0.10–0.50%
Category
chelating-agent
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1200919
ChEMBL Phase
Not listed
Adverse Events
2
Bioactivity
1
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E576 — ADI: NOT SPECIFIED mg/kg bw
View full food safety profile →Frequently Asked Questions
What regulatory lists include Sodium D-gluconate?
Sodium D-gluconate appears on 9 regulatory/inventory lists including inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, Europe; supplements, and 6 more. Source: EPA CPDat.
Is Sodium D-gluconate used in cosmetics?
Yes, Sodium D-gluconate is also indexed as a cosmetic ingredient under the name Sodium Gluconate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium D-gluconate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Sodium D-gluconate used outside industrial chemicals?
Sodium D-gluconate also appears in cosmetics, pharmaceutical, food safety databases.