What is the NOAEL for 2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine?
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine has 4 NOAEL studies in the database. The lowest reported value is 12M0RVW018 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine
CAS 50610-28-1
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine (CAS 50610-28-1) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for 2-Chloro-5-Nitro-N-Hydroxyethyl P-Phenylenediamine →
Cross-Vertical Regulatory Divergence
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine is prohibited in EU cosmetics but has active industrial GHS classifications (H317).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine
CAS Number
50610-28-1
DTXSID
DTXSID90866157
Molecular Formula
C8H10ClN3O3
InChI Key
QNJWQAYYVNKOKR-UHFFFAOYSA-N
Monoisotopic Mass
231.041069
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Dye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| banned; Europe; Personal care | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 12M0RVW018 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 12M0RVW018 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 12M0RVW018 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 12M0RVW018 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorant
Frequently Asked Questions
What regulatory lists include 2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine?
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine appears on 2 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), banned; Europe; Personal care. Source: EPA CPDat.
Is 2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine used in cosmetics?
Yes, 2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine is also indexed as a cosmetic ingredient under the name 2-Chloro-5-Nitro-N-Hydroxyethyl P-Phenylenediamine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does 2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine have different safety status in cosmetics vs industrial chemicals?
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine is prohibited in EU cosmetics but has active industrial GHS classifications (H317).
Is 2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine used outside industrial chemicals?
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine also appears in cosmetics databases.