What is the NOAEL for 1,4-Dioxane-2,5-dione?
1,4-Dioxane-2,5-dione has 4 NOAEL studies in the database. The lowest reported value is YRZ676PGU6 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
1,4-Dioxane-2,5-dione
Also known as: EINECS 207-954-9, Glycollide, NSC 403079, UNII-YRZ676PGU6
CAS 502-97-6
1,4-Dioxane-2,5-dione (CAS 502-97-6) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
1,4-Dioxane-2,5-dione
CAS Number
502-97-6
DTXSID
DTXSID8060115
Molecular Formula
C4H4O4
InChI Key
RKDVKSZUMVYZHH-UHFFFAOYSA-N
Monoisotopic Mass
116.010959
Synonyms
EINECS 207-954-9GlycollideNSC 403079UNII-YRZ676PGU6
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
HumectantSoftener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| YRZ676PGU6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| YRZ676PGU6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| YRZ676PGU6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| YRZ676PGU6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 1,4-dioxane-2,5-dione | 207-954-9 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Frequently Asked Questions
Is 1,4-Dioxane-2,5-dione used in cosmetics?
Yes, 1,4-Dioxane-2,5-dione is also indexed as a cosmetic ingredient under the name Glycolide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1,4-Dioxane-2,5-dione come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 1,4-Dioxane-2,5-dione used outside industrial chemicals?
1,4-Dioxane-2,5-dione also appears in cosmetics databases.