What is the NOAEL for Serotonin?
Serotonin has 4 NOAEL studies in the database. The lowest reported value is 333DO1RDJY UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Serotonin
Also known as: 5-22-12-00016, 3-(beta-Aminoethyl)-5-hydroxyindole, BRN 0143524, EINECS 200-058-9, Hippophain (+13 more)
CAS 50-67-9
Serotonin (CAS 50-67-9) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
Cross-Vertical Regulatory Divergence
Serotonin is prohibited in EU cosmetics but has active industrial GHS classifications (H301, H361).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
24 fields
Name
Serotonin
CAS Number
50-67-9
DTXSID
DTXSID8075330
Molecular Formula
C10H12N2O
InChI Key
QZAYGJVTTNCVMB-UHFFFAOYSA-N
Monoisotopic Mass
176.094963
Synonyms
5-22-12-000163-(beta-Aminoethyl)-5-hydroxyindoleBRN 0143524EINECS 200-058-9Hippophain5-Hydroxy-3-(beta-aminoethyl)indoleSubstanz DSUNII-333DO1RDJY3-(2-azanylethyl)-1H-indol-5-ol3-(b-Aminoethyl)-5-hydroxyindole5-HT5-HTA
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 333DO1RDJY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 333DO1RDJY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 333DO1RDJY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 333DO1RDJY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
SEROTONIN
ChEMBL Phase
3
Adverse Events
1
Bioactivity
9
Frequently Asked Questions
What regulatory lists include Serotonin?
Serotonin appears on 2 regulatory/inventory lists including active_ingredient; animal_products; Europe; pharmaceutical; residue, Canada; pharmaceutical. Source: EPA CPDat.
Is Serotonin used in cosmetics?
Yes, Serotonin is also indexed as a cosmetic ingredient under the name Serotonin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Serotonin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Serotonin have different safety status in cosmetics vs industrial chemicals?
Serotonin is prohibited in EU cosmetics but has active industrial GHS classifications (H301, H361).
Is Serotonin used outside industrial chemicals?
Serotonin also appears in cosmetics, pharmaceutical databases.