What is the NOAEL for 2,5-Cyclohexadiene-1,4-dione, 2-methyl-5-(1-methylethyl)-?
2,5-Cyclohexadiene-1,4-dione, 2-methyl-5-(1-methylethyl)- has 4 NOAEL studies in the database. The lowest reported value is O60IE26NUF UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2,5-Cyclohexadiene-1,4-dione, 2-methyl-5-(1-methylethyl)-
Also known as: BRN 1939047, 2,5-Cyclohexadiene-1,4-dione, 5-isopropyl-2-methyl-, p-Cymene-2,5-dione, EINECS 207-721-1, NSC 2228 (+1 more)
CAS 490-91-5
2,5-Cyclohexadiene-1,4-dione, 2-methyl-5-(1-methylethyl)- (CAS 490-91-5) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB.
SOURCE
NOAEL studies
NOAEL studies
4
SOURCE
Chemical inventory jurisdictions
Regulatory lists
0
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
2,5-Cyclohexadiene-1,4-dione, 2-methyl-5-(1-methylethyl)-
CAS Number
490-91-5
DTXSID
DTXSID9060079
Molecular Formula
C10H12O2
InChI Key
KEQHJBNSCLWCAE-UHFFFAOYSA-N
Monoisotopic Mass
164.08373
Synonyms
BRN 19390472,5-Cyclohexadiene-1,4-dione, 5-isopropyl-2-methyl-p-Cymene-2,5-dioneEINECS 207-721-1NSC 2228Thymoquinon
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| O60IE26NUF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O60IE26NUF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O60IE26NUF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O60IE26NUF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
THYMOQUINONE
ChEMBL Phase
2
Adverse Events
0
Bioactivity
3
Frequently Asked Questions
Is 2,5-Cyclohexadiene-1,4-dione, 2-methyl-5-(1-methylethyl)- used in cosmetics?
Yes, 2,5-Cyclohexadiene-1,4-dione, 2-methyl-5-(1-methylethyl)- is also indexed as a cosmetic ingredient under the name Thymoquinone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2,5-Cyclohexadiene-1,4-dione, 2-methyl-5-(1-methylethyl)- come from?
Safety data is sourced from EPA ToxValDB, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 2,5-Cyclohexadiene-1,4-dione, 2-methyl-5-(1-methylethyl)- used outside industrial chemicals?
2,5-Cyclohexadiene-1,4-dione, 2-methyl-5-(1-methylethyl)- also appears in cosmetics, pharmaceutical databases.