NOAEL Data Cosmetic Ingredient

Benzoic acid, 2,5-dihydroxy-

Also known as: 4-10-00-01441, BRN 2209119, EINECS 207-718-5, Gentisate, Salicylic acid, 5-hydroxy- (+13 more)

CAS 490-79-9

Benzoic acid, 2,5-dihydroxy- (CAS 490-79-9) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Gentisic Acid →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 24 fields
Name
Benzoic acid, 2,5-dihydroxy-
CAS Number
490-79-9
DTXSID
DTXSID4060078
Molecular Formula
C7H6O4
InChI Key
WXTMDXOMEHJXQO-UHFFFAOYSA-N
Monoisotopic Mass
154.026609
Synonyms
4-10-00-01441BRN 2209119EINECS 207-718-5GentisateSalicylic acid, 5-hydroxy-Acido 2,5-diidrossibenzoicoAcidum gentisicumKyselina 2,5-dihydroxybenzoovaKyselina gentisinovaUNII-VP36V95O3T2,5-Dioxybenzoate3,6-Dihydroxybenzoate

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Softener and conditioner

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
pharmaceuticalUS International Trade CommissionCPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
VP36V95O3TUNIIFDA UNII substance identifier--openFDA substances
VP36V95O3TUNIIFDA UNII substance identifier--openFDA substances
VP36V95O3TUNIIFDA UNII substance identifier--openFDA substances
VP36V95O3TUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
antioxidant
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL GENTISIC ACID
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
12
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Benzoic acid, 2,5-dihydroxy-?

Benzoic acid, 2,5-dihydroxy- has 4 NOAEL studies in the database. The lowest reported value is VP36V95O3T UNII. Source: openFDA substances.

What regulatory lists include Benzoic acid, 2,5-dihydroxy-?

Benzoic acid, 2,5-dihydroxy- appears on 1 regulatory/inventory list including pharmaceutical. Source: EPA CPDat.

Is Benzoic acid, 2,5-dihydroxy- used in cosmetics?

Yes, Benzoic acid, 2,5-dihydroxy- is also indexed as a cosmetic ingredient under the name Gentisic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Benzoic acid, 2,5-dihydroxy- come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Benzoic acid, 2,5-dihydroxy- used outside industrial chemicals?

Benzoic acid, 2,5-dihydroxy- also appears in cosmetics, pharmaceutical databases.