What is the NOAEL for 1-(2,5-Dihydroxyphenyl)ethanone?
1-(2,5-Dihydroxyphenyl)ethanone has 4 NOAEL studies in the database. The lowest reported value is K1H7QH11ZH UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
1-(2,5-Dihydroxyphenyl)ethanone
Also known as: Ethanone, 1-(2,5-dihydroxyphenyl)-, Acetophenone, 2′,5′-dihydroxy-, 1-(2,5-Dihydroxyphenyl)ethan-1-one, 1-Acetyl-2,5-dihydroxybenzene, 2,5-Dihydroxy-1-acetylbenzene (+13 more)
CAS 490-78-8
1-(2,5-Dihydroxyphenyl)ethanone (CAS 490-78-8) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
24 fields
Name
1-(2,5-Dihydroxyphenyl)ethanone
CAS Number
490-78-8
DTXSID
DTXSID9060077
Molecular Formula
C8H8O3
InChI Key
WLDWSGZHNBANIO-UHFFFAOYSA-N
Monoisotopic Mass
152.047344
Synonyms
Ethanone, 1-(2,5-dihydroxyphenyl)-Acetophenone, 2′,5′-dihydroxy-1-(2,5-Dihydroxyphenyl)ethan-1-one1-Acetyl-2,5-dihydroxybenzene2,5-Dihydroxy-1-acetylbenzene2-Acetyl-1,4-benzenediol2-Acetylhydroquinone2′,5′-DihydroxyacetophenoneQuinacetophenone4-08-00-01803AcetylhydroquinoneBRN 0637903
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
AntioxidantSoftener and conditionerBleaching agent
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| K1H7QH11ZH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K1H7QH11ZH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K1H7QH11ZH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K1H7QH11ZH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL2348532
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
Is 1-(2,5-Dihydroxyphenyl)ethanone used in cosmetics?
Yes, 1-(2,5-Dihydroxyphenyl)ethanone is also indexed as a cosmetic ingredient under the name 2-Acetylhydroquinone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1-(2,5-Dihydroxyphenyl)ethanone come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 1-(2,5-Dihydroxyphenyl)ethanone used outside industrial chemicals?
1-(2,5-Dihydroxyphenyl)ethanone also appears in cosmetics, pharmaceutical databases.