What is the NOAEL for Jasmone?
Jasmone has 11 NOAEL studies in the database. The lowest reported value is 4.514 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Jasmone
Also known as: 4-07-00-00337, BRN 1907713, EINECS 207-668-4, FEMA No. 3196, 3-Methyl-2-(cis-2-penten-1-yl)-2-cyclopenten-1-one (+2 more)
CAS 488-10-8
Jasmone (CAS 488-10-8) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
11
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Jasmone
CAS Number
488-10-8
DTXSID
DTXSID4047092
Molecular Formula
C11H16O
InChI Key
XMLSXPIVAXONDL-PLNGDYQASA-N
Monoisotopic Mass
164.120115
Synonyms
4-07-00-00337BRN 1907713EINECS 207-668-4FEMA No. 31963-Methyl-2-(cis-2-penten-1-yl)-2-cyclopenten-1-one3-Methyl-2-(2-pentenyl)-2-cyclopenten-1-one, (Z)-UNII-RC4W0G9YUK
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
20 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| consumer_product | P&G | Proctor & Gamble |
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 11 of 11 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =4.514 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| RC4W0G9YUK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RC4W0G9YUK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RC4W0G9YUK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RC4W0G9YUK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 620 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 5400 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
| 4 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 11 of 11 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3-methyl-2-pent-2-enylcyclopent-2-enone | 207-668-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CIS-JASMONE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Jasmone?
Jasmone appears on 5 regulatory/inventory lists including consumer_product, Europe, IFRA Transparency, and 2 more. Source: EPA CPDat.
Is Jasmone used in cosmetics?
Yes, Jasmone is also indexed as a cosmetic ingredient under the name cis-Jasmone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Jasmone come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Jasmone used outside industrial chemicals?
Jasmone also appears in cosmetics, pharmaceutical, cannabis databases.