EFSA toxicology reference values
3-Methyl-2(pent-2-enyl)cyclopent-2-en-1-one
SOURCE
efsa openfoodtox 3 0 export repository
3-Methyl-2(pent-2-enyl)cyclopent-2-en-1-one (CAS 488-10-8). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
3-Methyl-2(pent-2-enyl)cyclopent-2-en-1-one is a cannabis analyte contaminant represented in the cannabis public dataset.
CAS 488-10-8
Cannabis Analyte
Substance Identity
Analyte identity and classification used for this cannabis substance page.
SOURCE
efsa substances
Analyte name
3-Methyl-2(pent-2-enyl)cyclopent-2-en-1-one
CAS number
488-10-8
Contaminant class
Cannabis Analyte
Contaminant Class Badge
Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.
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State Cannabis Regulations
Cannabis Analyte
Cannabis contaminant class used to group state testing rows.
Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
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cannabis page data
Quality score
2
thin
Jurisdictions
0
No state rows
Lab/analyte rows
0
0 failed (-)
Potency samples
0
488-10-8
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
SOURCE
efsa openfoodtox 3 0 export repository
3-Methyl-2(pent-2-enyl)cyclopent-2-en-1-one
CAS 488-10-8 / mono-constituent substance
C11H16O / 6 dossier(s)
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
SOURCE
efsa openfoodtox 3 0 export repository
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| MSI/FC | 0.3 mg/kg | other: | - | - |
| MSI/FC | 0.3 mg/kg | other: | - | - |
| MSI/FC | 0.5 mg/kg | other: | - | - |
| MSI/FC | 0.5 mg/kg | salmon | - | - |
| MSI/FC | 0.5 mg/kg | other: | - | - |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | other: |
| margin of safety | - | consumers | - | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
SOURCE
efsa openfoodtox 3 0 export repository
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| Carcinogenicity_EU_PPP | - | - | - | The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advise for the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation 212 (FGE.212) concerns 23 substances which correspond to subgroup 2.6 of FGE.19. Fifteen of these substances are alpha,beta-unsaturated alicyclic ketones [FL-no: 07.033, 07.035, 07.094, 07.098, 07.112, 07.126, 07.129, 07.140, 7.146, 07.147, 07.172, 07.175, 07.196, 07.202 and 07.255] and eight are precursors for such ketones [FL-no: 02.062, 02.083, 02.101, 02.214, 09.143, 09.215, 09.821 and 09.870]. |
| Carcinogenicity_EU_PPP | - | - | - | Authority was requested to evaluate the genotoxic potential of 22 flavouring substances from subgroup 2.6 of FGE.19 in the Flavouring Group Evaluation 212. Based on available genotoxicity data and new genotoxicity data submitted by the Industry, the Panel concluded that genotoxic potential could be ruled out for the six carvone derivatives [FL-no: 02.062, 07.146, 07.147, 09.143, 09.215 and 09.870], the 11 isophorone derivatives [FL-no: 02.083, 02.101, 07.035, 07.098, 07.126, 07.129, 07.172, 07.175, 07.196, 07.202 and 07.255] and the five substances [FL-no: 07.033, 07.094, 07.112, 07.140 and 07.219] from subgroup 2.6 in FGE.212, FGE.212Rev1 and FGE.212Rev3, respectively. Two substances previously included in FGE.212Rev2, vetiverol and vetiveryl acetate [FL-no: 02.214 and 09.821], are no longer supported by Industry. Based on the available data, all 22 substances of this FGE are no longer of concern with respect to genotoxicity and can be evaluated through the Procedure. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present revision of FGE.51, FGE.51Rev2, is due to new genotoxicity data evaluated in FGE.212Rev3 (EFSA CEF Panel, 2015a), which deals only with the genotoxic potential of alpha,beta-unsaturated flavouring substances. Based on these data, the Panel concluded that the data available could rule out the concern for genotoxicity for [FL-no: 07.033, 07.094, 07.112 and 07.140] and accordingly these substances can be evaluated through the Procedure in this revision. |
| Carcinogenicity_EU_PPP | - | - | - | The European Food Safety Authority (EFSA) asked the Scientific Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. In the present revision of FGE.212, FGE.212Rev1, there has been a reassessment of [FL-no: 02.083, 02.101, 07.033, 07.035, 07.094, 07.098, 07.112, 07.129, 07.140, 07.172, 07.175, 07.196, 07.202 and 07.255] for which there were a request for genotoxicity data in FGE.212. Flavouring Group Evaluation 212 (FGE.212) concerns 23 substances. The 23 substances correspond to subgroup 2.6 of FGE.19. Fifteen of these substances are alpha,beta-unsaturated alicyclic ketones and eight are precursors for such ketones. |
| Carcinogenicity_EU_PPP | - | - | - | The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 24 flavouring substances from subgroup 2.6 of FGE.19 in the Flavouring Group Evaluation 212, Revision 2. The Panel concluded in FGE.212, that the genotoxic potential could be ruled out for d-carvone [FL-no: 07.146] together with the structurally related l-carvone [FL-no: 07.147] as well as carveol and the carvyl derivatives [FL-no: 02.062, 09.143, 09.215 and 09.870]. Based on available genotoxicity data and new submitted genotoxicity data from the Industry, the Panel concluded that the genotoxic potential could be ruled out for the 11 isophorone derivatives [FL-no: 02.083, 02.101, 07.035, 07.098, 07.126, 07.129, 07.172, 07.175, 07.196, 07.202 and 07.255] and the two vetiveryl derivatives [FL-no: 02.214 and 09.821] in FGE.212Rev1 and FGE.212Rev2, respectively. For the remaining five substances [FL-no: 07.033, 07.094, 07.112, 07.140 and 07.219] from subgroup 2.6 there is still a genotoxicity concern and additional data are required. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the European Food Safety Authority (EFSA) Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 29 compounds (secondary alicyclic saturated and unsaturated alcohols/ketones/ketals/esters with ketals containing alicyclic alcohols or ketones and esters containing secondary alicyclic alcohols) belonging to chemical group 8. |
| Genetic Toxicity | - | - | - | Following a request from the European Commission, the European Food Safety Authority (EFSA) Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 29 compounds (secondary alicyclic saturated and unsaturated alcohols/ketones/ketals/esters with ketals containing alicyclic alcohols or ketones and esters containing secondary alicyclic alcohols) belonging to chemical group 8. |
| Genetic Toxicity | - | - | - | The European Food Safety Authority (EFSA) asked the Scientific Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. In the present revision of FGE.212, FGE.212Rev1, there has been a reassessment of [FL-no: 02.083, 02.101, 07.033, 07.035, 07.094, 07.098, 07.112, 07.129, 07.140, 07.172, 07.175, 07.196, 07.202 and 07.255] for which there were a request for genotoxicity data in FGE.212. Flavouring Group Evaluation 212 (FGE.212) concerns 23 substances. The 23 substances correspond to subgroup 2.6 of FGE.19. Fifteen of these substances are alpha,beta-unsaturated alicyclic ketones and eight are precursors for such ketones. |
| Genetic Toxicity | - | - | - | Following a request from the European commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present revision of FGE.51, FGE.51Rev2, is due to new genotoxicity data evaluated in FGE.212Rev3 (EFSA CEF Panel, 2015a), which deals only with the genotoxic potential of alpha,beta-unsaturated flavouring substances. Based on these data, the Panel concluded that the data available could rule out the concern for genotoxicity for [FL-no: 07.033, 07.094, 07.112 and 07.140] and accordingly these substances can be evaluated through the Procedure in this revision. |
| Genetic Toxicity | - | - | - | Authority was requested to evaluate the genotoxic potential of 22 flavouring substances from subgroup 2.6 of FGE.19 in the Flavouring Group Evaluation 212. Based on available genotoxicity data and new genotoxicity data submitted by the Industry, the Panel concluded that genotoxic potential could be ruled out for the six carvone derivatives [FL-no: 02.062, 07.146, 07.147, 09.143, 09.215 and 09.870], the 11 isophorone derivatives [FL-no: 02.083, 02.101, 07.035, 07.098, 07.126, 07.129, 07.172, 07.175, 07.196, 07.202 and 07.255] and the five substances [FL-no: 07.033, 07.094, 07.112, 07.140 and 07.219] from subgroup 2.6 in FGE.212, FGE.212Rev1 and FGE.212Rev3, respectively. Two substances previously included in FGE.212Rev2, vetiverol and vetiveryl acetate [FL-no: 02.214 and 09.821], are no longer supported by Industry. Based on the available data, all 22 substances of this FGE are no longer of concern with respect to genotoxicity and can be evaluated through the Procedure. |
| Genetic Toxicity | - | - | - | The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advise for the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation 212 (FGE.212) concerns 23 substances which correspond to subgroup 2.6 of FGE.19. Fifteen of these substances are alpha,beta-unsaturated alicyclic ketones [FL-no: 07.033, 07.035, 07.094, 07.098, 07.112, 07.126, 07.129, 07.140, 7.146, 07.147, 07.172, 07.175, 07.196, 07.202 and 07.255] and eight are precursors for such ketones [FL-no: 02.062, 02.083, 02.101, 02.214, 09.143, 09.215, 09.821 and 09.870]. |
| Genetic Toxicity | - | - | - | The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 24 flavouring substances from subgroup 2.6 of FGE.19 in the Flavouring Group Evaluation 212, Revision 2. The Panel concluded in FGE.212, that the genotoxic potential could be ruled out for d-carvone [FL-no: 07.146] together with the structurally related l-carvone [FL-no: 07.147] as well as carveol and the carvyl derivatives [FL-no: 02.062, 09.143, 09.215 and 09.870]. Based on available genotoxicity data and new submitted genotoxicity data from the Industry, the Panel concluded that the genotoxic potential could be ruled out for the 11 isophorone derivatives [FL-no: 02.083, 02.101, 07.035, 07.098, 07.126, 07.129, 07.172, 07.175, 07.196, 07.202 and 07.255] and the two vetiveryl derivatives [FL-no: 02.214 and 09.821] in FGE.212Rev1 and FGE.212Rev2, respectively. For the remaining five substances [FL-no: 07.033, 07.094, 07.112, 07.140 and 07.219] from subgroup 2.6 there is still a genotoxicity concern and additional data are required. |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
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Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
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page FAQ dataset
What is the regulatory limit for 3-Methyl-2(pent-2-enyl)cyclopent-2-en-1-one in cannabis?
3-Methyl-2(pent-2-enyl)cyclopent-2-en-1-one does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for 3-Methyl-2(pent-2-enyl)cyclopent-2-en-1-one?
3-Methyl-2(pent-2-enyl)cyclopent-2-en-1-one does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for 3-Methyl-2(pent-2-enyl)cyclopent-2-en-1-one?
3-Methyl-2(pent-2-enyl)cyclopent-2-en-1-one has 11 EFSA OpenFoodTox reference value rows in the cannabis database, including MSI/FC, TTC Cramer Class II, margin of safety.
Is 3-Methyl-2(pent-2-enyl)cyclopent-2-en-1-one also regulated in cosmetics or food?
3-Methyl-2(pent-2-enyl)cyclopent-2-en-1-one does not have a cosmetics ingredient cross-reference in the fetched page data. EFSA food/toxicology context is available on this page.