What is the NOAEL for 2-Hydroxy-4-(methylthio)-butanoic acid calcium salt (2:1)?
2-Hydroxy-4-(methylthio)-butanoic acid calcium salt (2:1) has 4 NOAEL studies in the database. The lowest reported value is 1VK0YS654L UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2-Hydroxy-4-(methylthio)-butanoic acid calcium salt (2:1)
Also known as: Calcium bis((1)-2-hydroxy-4-(methylthio)butyrate), Butanoic acid, 2-hydroxy-4-(methylthio)-, calcium salt (2:1), Calcium DL-2-hydroxy-4-methylthiobutyrate, Calcium DL-alpha-hydroxy-gamma-methylthiobutyrate, Calcium alpha-hydroxy-gamma-methylmercaptobutyrate (+8 more)
CAS 4857-44-7
2-Hydroxy-4-(methylthio)-butanoic acid calcium salt (2:1) (CAS 4857-44-7) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
View cosmetic safety profile for Calcium Hydroxymethionine →
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
19 fields
Name
2-Hydroxy-4-(methylthio)-butanoic acid calcium salt (2:1)
CAS Number
4857-44-7
DTXSID
DTXSID80919308
Molecular Formula
2C5H10O3S.Ca
InChI Key
ABRVDWASZFDIEH-UHFFFAOYSA-L
Monoisotopic Mass
340.032722
Synonyms
Calcium bis((1)-2-hydroxy-4-(methylthio)butyrate)Butanoic acid, 2-hydroxy-4-(methylthio)-, calcium salt (2:1)Calcium DL-2-hydroxy-4-methylthiobutyrateCalcium DL-alpha-hydroxy-gamma-methylthiobutyrateCalcium alpha-hydroxy-gamma-methylmercaptobutyrateD-L-alpha-Hydroxylmethionine calciumDL-Methioninehydroxyanalog calciumMethionine hydroxyl analog calcium salt2-Hydroxy-4-(methylthio)butyric acid calcium saltHydanHydan (methionine hydroxy analog)MHA
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 1VK0YS654L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1VK0YS654L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1VK0YS654L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1VK0YS654L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
Is 2-Hydroxy-4-(methylthio)-butanoic acid calcium salt (2:1) used in cosmetics?
Yes, 2-Hydroxy-4-(methylthio)-butanoic acid calcium salt (2:1) is also indexed as a cosmetic ingredient under the name Calcium Hydroxymethionine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Hydroxy-4-(methylthio)-butanoic acid calcium salt (2:1) come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Hydroxy-4-(methylthio)-butanoic acid calcium salt (2:1) used outside industrial chemicals?
2-Hydroxy-4-(methylthio)-butanoic acid calcium salt (2:1) also appears in cosmetics, cannabis databases.