What is the NOAEL for Chrysin?
Chrysin has 10 NOAEL studies in the database. The lowest reported value is 7.60425745582621 uM. Source: NTP_ICE_endocrine.
NOAEL Data
Cosmetic Ingredient
Chrysin
Also known as: 5-18-04-00076, BRN 0233276, 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one, EINECS 207-549-7, UNII-3CN01F5ZJ5 (+1 more)
CAS 480-40-0
Chrysin (CAS 480-40-0) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
10
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Chrysin
CAS Number
480-40-0
DTXSID
DTXSID1022396
Molecular Formula
C15H10O4
InChI Key
RTIXKCRFFJGDFG-UHFFFAOYSA-N
Monoisotopic Mass
254.057909
Synonyms
5-18-04-00076BRN 02332765,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-oneEINECS 207-549-7UNII-3CN01F5ZJ55,7-Dihydroxy-2-phenyl-4H-benzo(b)pyran-4-one
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 10.7043553773797 | uM | AC50 | - | - | NTP_ICE_endocrine |
| 7.60425745582621 | uM | ACC | - | - | NTP_ICE_endocrine |
| 204 | uL/min/10^6 cells | Clint | - | Human | NTP_ICE_adme_parameters |
| 3CN01F5ZJ5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3CN01F5ZJ5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3CN01F5ZJ5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3CN01F5ZJ5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.00263 | fraction | Fu | - | Human | NTP_ICE_adme_parameters |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| 0.134 | unitless | Model Score | - | - | NTP_ICE_endocrine |
Showing 10 of 10 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHRYSIN
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
10
Frequently Asked Questions
What regulatory lists include Chrysin?
Chrysin appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.
Is Chrysin used in cosmetics?
Yes, Chrysin is also indexed as a cosmetic ingredient under the name Chrysin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Chrysin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Chrysin used outside industrial chemicals?
Chrysin also appears in cosmetics, pharmaceutical databases.