What is the NOAEL for (3,3-Dimethoxypropen-1-yl)benzene?
(3,3-Dimethoxypropen-1-yl)benzene has 10 NOAEL studies in the database. The lowest reported value is 1.667 % via Dermal in Human. Source: NTP ICE skin sensitization.
NOAEL Data
Cosmetic Ingredient
(3,3-Dimethoxypropen-1-yl)benzene
Also known as: Cinnamaldehyde dimethyl acetyl, Cinnamic aldehyde dimethyl acetal, 3-Phenyl-2-propenal dimethyl acetal, 3,3-Dimethoxy-1-phenylprop-1-ene, Benzene, (3,3-dimethoxy-1-propenyl)- (+3 more)
CAS 4364-06-1
(3,3-Dimethoxypropen-1-yl)benzene (CAS 4364-06-1) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Cinnamaldehyde Dimethyl Acetal →
SOURCE
NOAEL studies
NOAEL studies
10
SOURCE
Chemical inventory jurisdictions
Regulatory lists
1
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
(3,3-Dimethoxypropen-1-yl)benzene
CAS Number
4364-06-1
DTXSID
DTXSID1063433
Molecular Formula
C11H14O2
InChI Key
MBAOABFNWSOOLU-UHFFFAOYSA-N
Monoisotopic Mass
178.09938
Synonyms
Cinnamaldehyde dimethyl acetylCinnamic aldehyde dimethyl acetal3-Phenyl-2-propenal dimethyl acetal3,3-Dimethoxy-1-phenylprop-1-eneBenzene, (3,3-dimethoxy-1-propenyl)-Benzene, (3,3-dimethoxy-1-propen-1-yl)-(3,3-Dimethoxy-1-propenyl)benzeneEINECS 224-454-6
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
2 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 2.083 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 1.667 | % | Concentration, one positive response | Dermal | Human | NTP ICE skin sensitization |
| V01GQ3W5KQ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V01GQ3W5KQ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 24 | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 6480 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| 1350 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 1080 | ug/cm2 | Induction dose per skin area, one positive response | Dermal | Human | NTP ICE skin sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
Showing 10 of 10 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include (3,3-Dimethoxypropen-1-yl)benzene?
(3,3-Dimethoxypropen-1-yl)benzene appears on 1 regulatory/inventory list including IFRA Transparency. Source: EPA CPDat.
Is (3,3-Dimethoxypropen-1-yl)benzene used in cosmetics?
Yes, (3,3-Dimethoxypropen-1-yl)benzene is also indexed as a cosmetic ingredient under the name Cinnamaldehyde Dimethyl Acetal. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for (3,3-Dimethoxypropen-1-yl)benzene come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is (3,3-Dimethoxypropen-1-yl)benzene used outside industrial chemicals?
(3,3-Dimethoxypropen-1-yl)benzene also appears in cosmetics databases.