NOAEL Data REACH Registered Cosmetic Ingredient

Disodium isodecyl sulfosuccinate

Also known as: Butanedioic acid, sulfo-, 4-isodecyl ester, disodium salt, EINECS 253-452-8

CAS 37294-49-8

Disodium isodecyl sulfosuccinate (CAS 37294-49-8) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Disodium Isodecyl Sulfosuccinate →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 8 fields

Name

Disodium isodecyl sulfosuccinate

CAS Number

37294-49-8

DTXSID

DTXSID5044237

Molecular Formula

C14H26O7S.2Na

InChI Key

XGWOIOIVSZIIKJ-UHFFFAOYSA-L

Monoisotopic Mass

384.119463

Synonyms

Butanedioic acid, sulfo-, 4-isodecyl ester, disodium saltEINECS 253-452-8

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 6 records

Surfactant (surface active agent)Solubility enhancerSoftener and conditionerCleaning agentFoamant

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records

List	Keyword	Source
inert_ingredient; non_food_use; Pesticides	EPA	CPCat
Indirect additives food contact (10/2018)	FDA	United States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 6 of 6 studies

Value	Unit	Endpoint	Route	Species	Source
=46.67	mg/m3	DNEL systemic	inhalation	Human	ToxValDB_GESTIS_DNEL
83A1X0BVF4	UNII	FDA UNII substance identifier	-	-	openFDA substances
83A1X0BVF4	UNII	FDA UNII substance identifier	-	-	openFDA substances
83A1X0BVF4	UNII	FDA UNII substance identifier	-	-	openFDA substances
83A1X0BVF4	UNII	FDA UNII substance identifier	-	-	openFDA substances
=300	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID

Showing 6 of 6 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	Disodium C-isodecyl sulphonatosuccinate	253-452-8	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Frequently Asked Questions

What is the NOAEL for Disodium isodecyl sulfosuccinate?

Disodium isodecyl sulfosuccinate has 6 NOAEL studies in the database. The lowest reported value is 46.67 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include Disodium isodecyl sulfosuccinate?

Disodium isodecyl sulfosuccinate appears on 2 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, Indirect additives food contact (10/2018). Source: EPA CPDat.

Is Disodium isodecyl sulfosuccinate used in cosmetics?

Yes, Disodium isodecyl sulfosuccinate is also indexed as a cosmetic ingredient under the name Disodium Isodecyl Sulfosuccinate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Disodium isodecyl sulfosuccinate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Disodium isodecyl sulfosuccinate used outside industrial chemicals?

Disodium isodecyl sulfosuccinate also appears in cosmetics databases.