What is the NOAEL for 2-Phenylethyl methacrylate?
2-Phenylethyl methacrylate has 9 NOAEL studies in the database. The lowest reported value is 5VLG348MDF UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2-Phenylethyl methacrylate
Also known as: 2-Propenoic acid, 2-methyl-, 2-phenylethyl ester, 3-06-00-01710, BRN 2329237, EINECS 222-969-0, beta-Phenylethyl methacrylate (+2 more)
CAS 3683-12-3
2-Phenylethyl methacrylate (CAS 3683-12-3) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
NOAEL studies
NOAEL studies
9
SOURCE
Chemical inventory jurisdictions
Regulatory lists
0
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
2-Phenylethyl methacrylate
CAS Number
3683-12-3
DTXSID
DTXSID7063134
Molecular Formula
C12H14O2
InChI Key
ILZXXGLGJZQLTR-UHFFFAOYSA-N
Monoisotopic Mass
190.09938
Synonyms
2-Propenoic acid, 2-methyl-, 2-phenylethyl ester3-06-00-01710BRN 2329237EINECS 222-969-0beta-Phenylethyl methacrylatebeta-Phenylethyl 2-methylpropenatePhenylethyl 2-methyl-2-propenoate
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
1 records
Fragrance
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 5VLG348MDF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5VLG348MDF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5VLG348MDF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5VLG348MDF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 775 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| 4050 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
Showing 9 of 9 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
Is 2-Phenylethyl methacrylate used in cosmetics?
Yes, 2-Phenylethyl methacrylate is also indexed as a cosmetic ingredient under the name Phenethyl Methacrylate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Phenylethyl methacrylate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Phenylethyl methacrylate used outside industrial chemicals?
2-Phenylethyl methacrylate also appears in cosmetics databases.