NOAEL Data REACH Registered Cosmetic Ingredient

2,2-Bis{[(3-sulfanylpropanoyl)oxy]methyl}butyl 3-sulfanylpropanoate

Also known as: Propanoic acid, 3-mercapto-, 2-ethyl-2-[(3-mercapto-1-oxopropoxy)methyl]-1,3-propanediyl ester, Propanoic acid, 3-mercapto-, 1,1'-[2-ethyl-2-[(3-mercapto-1-oxopropoxy)methyl]-1,3-propanediyl] ester, 2-Ethyl-2-((3-mercapto-1-oxopropoxy)methyl)propane-1,3-diyl bis(3-mercaptopropionate), Trimethylolpropane tris(3-mercaptopropionate), Epicure QX 30 (+3 more)

CAS 33007-83-9

2,2-Bis{[(3-sulfanylpropanoyl)oxy]methyl}butyl 3-sulfanylpropanoate (CAS 33007-83-9) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Trimethylolpropane Tris-Mercaptopropionate →

SOURCE noael studies public
NOAEL studies
5
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 14 fields
Name
2,2-Bis{[(3-sulfanylpropanoyl)oxy]methyl}butyl 3-sulfanylpropanoate
CAS Number
33007-83-9
DTXSID
DTXSID8044919
Molecular Formula
C15H26O6S3
InChI Key
IMQFZQVZKBIPCQ-UHFFFAOYSA-N
Monoisotopic Mass
398.089152
Synonyms
Propanoic acid, 3-mercapto-, 2-ethyl-2-[(3-mercapto-1-oxopropoxy)methyl]-1,3-propanediyl esterPropanoic acid, 3-mercapto-, 1,1'-[2-ethyl-2-[(3-mercapto-1-oxopropoxy)methyl]-1,3-propanediyl] ester2-Ethyl-2-((3-mercapto-1-oxopropoxy)methyl)propane-1,3-diyl bis(3-mercaptopropionate)Trimethylolpropane tris(3-mercaptopropionate)Epicure QX 30EINECS 251-336-13-Mercaptopropanoic acid, 2-ethyl-2-(hydroxymethyl)-1,3-propanediol triester3-Mercaptopropionic acid triester with trimethylolpropane

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records
HardenerChemical reaction regulatorNo specific technical function

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 5 of 5 studies
ValueUnitEndpointRouteSpeciesSource
=1.97mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
BYN53W5D3LUNIIFDA UNII substance identifier--openFDA substances
BYN53W5D3LUNIIFDA UNII substance identifier--openFDA substances
BYN53W5D3LUNIIFDA UNII substance identifier--openFDA substances
BYN53W5D3LUNIIFDA UNII substance identifier--openFDA substances

Showing 5 of 5 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered2-ethyl-2-[(3-mercapto-1-oxopropoxy)methyl]propane-1,3-diyl bis[3-mercaptopropionate]251-336-1ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3182472
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for 2,2-Bis{[(3-sulfanylpropanoyl)oxy]methyl}butyl 3-sulfanylpropanoate?

2,2-Bis{[(3-sulfanylpropanoyl)oxy]methyl}butyl 3-sulfanylpropanoate has 5 NOAEL studies in the database. The lowest reported value is 1.97 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

Is 2,2-Bis{[(3-sulfanylpropanoyl)oxy]methyl}butyl 3-sulfanylpropanoate used in cosmetics?

Yes, 2,2-Bis{[(3-sulfanylpropanoyl)oxy]methyl}butyl 3-sulfanylpropanoate is also indexed as a cosmetic ingredient under the name Trimethylolpropane Tris-Mercaptopropionate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2,2-Bis{[(3-sulfanylpropanoyl)oxy]methyl}butyl 3-sulfanylpropanoate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is 2,2-Bis{[(3-sulfanylpropanoyl)oxy]methyl}butyl 3-sulfanylpropanoate used outside industrial chemicals?

2,2-Bis{[(3-sulfanylpropanoyl)oxy]methyl}butyl 3-sulfanylpropanoate also appears in cosmetics, pharmaceutical databases.