What is the NOAEL for Sodium pidolate?
Sodium pidolate has 8 NOAEL studies in the database. The lowest reported value is 141 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Sodium pidolate
Also known as: EINECS 249-277-1, L-5-Oxoproline monosodium salt, 5-Oxo-L-proline monosodium salt, UNII-1V74VH163T
CAS 28874-51-3
Sodium pidolate (CAS 28874-51-3) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
8
SOURCE
Chemical inventory jurisdictions
Regulatory lists
3
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
Sodium pidolate
CAS Number
28874-51-3
DTXSID
DTXSID50183074
Molecular Formula
C5H7NO3.Na
InChI Key
CRPCXAMJWCDHFM-DFWYDOINSA-M
Synonyms
EINECS 249-277-1L-5-Oxoproline monosodium salt5-Oxo-L-proline monosodium saltUNII-1V74VH163T
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
54 records
HumectantAnti-static agentSoftener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =141 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| 1V74VH163T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1V74VH163T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1V74VH163T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1V74VH163T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >2000 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| =7200 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =8200 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Sodium 5-oxo-L-prolinate | 249-277-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Other
Frequently Asked Questions
What regulatory lists include Sodium pidolate?
Sodium pidolate appears on 1 regulatory/inventory list including Europe; Personal care. Source: EPA CPDat.
Is Sodium pidolate used in cosmetics?
Yes, Sodium pidolate is also indexed as a cosmetic ingredient under the name Regulatory and. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium pidolate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Sodium pidolate used outside industrial chemicals?
Sodium pidolate also appears in cosmetics databases.