Also known as: 2-Propenoic acid, 2-methyl-, 2-(dimethylamino)ethyl ester, Methacrylic acid, 2-(dimethylamino)ethyl ester, Acryester DM, NSC 20959, 4-04-00-01432 (+7 more)
CAS 2867-47-2
2-(Dimethylamino)ethyl methacrylate (CAS 2867-47-2) is a chemical substance with GHS signal word Warning; key hazard signal: H312; H302; H315; H319; H317. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
View cosmetic safety profile for Dimethylaminoethyl Methacrylate (DMAEMA) →
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Acute Tox. 4 *; Acute Tox. 4 *; Skin Irrit. 2; Eye Irrit. 2; Skin Sens. 1 | H312; H302; H315; H319; H317 | GHS07 | Warning |
International Chemical Safety Card hazard and exposure summary.
| Field | Value |
|---|---|
| GHS Signal Word | DANGER |
| GHS Hazard Statements | Combustible liquid Causes severe skin burns and eye damage Harmful to aquatic life |
| Short-term Effects | The substance is corrosive to the eyes and skin. The substance is irritating to the respiratory tract. Corrosive on ingestion. |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =27 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| O0V97PV2G1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O0V97PV2G1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O0V97PV2G1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O0V97PV2G1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.62 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| =455 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =1550 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =1751 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| >2000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =200 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HPVIS |
| =643.001 | mg/m3 | NOAEL | inhalation | Rat | ToxValDB_HPVIS |
Showing 12 of 12 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-dimethylaminoethyl methacrylate | 220-688-8 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
2-(Dimethylamino)ethyl methacrylate (CAS 2867-47-2) is classified under EU CLP Annex VI as Acute Tox. 4 *; Acute Tox. 4 *; Skin Irrit. 2; Eye Irrit. 2; Skin Sens. 1 with signal word Warning. Hazard statements: H312; H302; H315; H319; H317. Source: EU CLP Annex VI (ECHA).
2-(Dimethylamino)ethyl methacrylate has 12 NOAEL studies in the database. The lowest reported value is 27 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
2-(Dimethylamino)ethyl methacrylate appears on 2 regulatory/inventory lists including drinking_water; Europe; manufacturing; plastic_additive, Indirect additives food contact (10/2018). Source: EPA CPDat.
Yes, 2-(Dimethylamino)ethyl methacrylate is also indexed as a cosmetic ingredient under the name Dimethylaminoethyl Methacrylate (DMAEMA). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
2-(Dimethylamino)ethyl methacrylate also appears in cosmetics, pharmaceutical databases.