What is the NOAEL for Choline glycerophosphate?
Choline glycerophosphate has 4 NOAEL studies in the database. The lowest reported value is 60M22SGW66 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Choline glycerophosphate
Also known as: Choline hydroxide, (R)-2,3-dihydroxypropyl hydrogen phosphate, inner salt, Choline, hydroxide, 2,3-dihydroxypropyl hydrogen phosphate, inner salt, D-, Ethanaminium, 2-(((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt, (R)-, Choline alfoscerate, Choline-alfoscerate (+2 more)
CAS 28319-77-9
Choline glycerophosphate (CAS 28319-77-9) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Choline glycerophosphate
CAS Number
28319-77-9
DTXSID
DTXSID70951010
Molecular Formula
C8H20NO6P
InChI Key
SUHOQUVVVLNYQR-MRVPVSSYSA-N
Monoisotopic Mass
257.102824
Synonyms
Choline hydroxide, (R)-2,3-dihydroxypropyl hydrogen phosphate, inner saltCholine, hydroxide, 2,3-dihydroxypropyl hydrogen phosphate, inner salt, D-Ethanaminium, 2-(((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt, (R)-Choline alfoscerateCholine-alfoscerateAlpha-GPCL-α-Glycerylphosphorylcholine
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| pharmaceutical | US International Trade Commission | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 60M22SGW66 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 60M22SGW66 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 60M22SGW66 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 60M22SGW66 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
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ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Choline glycerophosphate | 248-962-2 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1567463
ChEMBL Phase
Not listed
Adverse Events
35
Bioactivity
2
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
2 records
FDA GRAS: FDA has no questions
View full food safety profile →Frequently Asked Questions
What regulatory lists include Choline glycerophosphate?
Choline glycerophosphate appears on 2 regulatory/inventory lists including pharmaceutical, Canada; pharmaceutical. Source: EPA CPDat.
Is Choline glycerophosphate used in cosmetics?
Yes, Choline glycerophosphate is also indexed as a cosmetic ingredient under the name Glycerophosphocholine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Choline glycerophosphate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Choline glycerophosphate used outside industrial chemicals?
Choline glycerophosphate also appears in cosmetics, pharmaceutical, food safety databases.