What is the NOAEL for 3-Methoxybutan-1-ol?
3-Methoxybutan-1-ol has 6 NOAEL studies in the database. The lowest reported value is SJ995B41AO UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
3-Methoxybutan-1-ol
Also known as: 1-Butanol, 3-methoxy-, EINECS 219-741-8, 3-Methoxy-1-butanol, NSC 65580, UNII-SJ995B41AO
CAS 2517-43-3
3-Methoxybutan-1-ol (CAS 2517-43-3) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
3-Methoxybutan-1-ol is prohibited in EU cosmetics but has active industrial GHS classifications (H226).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
3-Methoxybutan-1-ol
CAS Number
2517-43-3
DTXSID
DTXSID0044812
Molecular Formula
C5H12O2
InChI Key
JSGVZVOGOQILFM-UHFFFAOYSA-N
Monoisotopic Mass
104.08373
Synonyms
1-Butanol, 3-methoxy-EINECS 219-741-83-Methoxy-1-butanolNSC 65580UNII-SJ995B41AO
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Solvent
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| SJ995B41AO | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| SJ995B41AO | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| SJ995B41AO | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| SJ995B41AO | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >2000 | mg/m3 | LEL | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =100 | mg/kg bw/day | NOAEL | injection | Guinea Pig | ToxValDB_ECHA_IUCLID |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3-methoxybutan-1-ol | 219-741-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Solvent
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3186019
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
Is 3-Methoxybutan-1-ol used in cosmetics?
Yes, 3-Methoxybutan-1-ol is also indexed as a cosmetic ingredient under the name 3-Methoxybutanol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3-Methoxybutan-1-ol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does 3-Methoxybutan-1-ol have different safety status in cosmetics vs industrial chemicals?
3-Methoxybutan-1-ol is prohibited in EU cosmetics but has active industrial GHS classifications (H226).
Is 3-Methoxybutan-1-ol used outside industrial chemicals?
3-Methoxybutan-1-ol also appears in cosmetics, pharmaceutical databases.