Warning GHS07GHS09 NOAEL Data REACH Registered Cosmetic Ingredient

Bisphenol A/ Epichlorohydrin resin

Also known as: Phenol, 4,4'-(1-methylethylidene)bis-, polymer with, Epidian, UP 5-207, Araldit LY 556, Bisphenol A epichlorohydrin polymer

CAS 25068-38-6

Bisphenol A/ Epichlorohydrin resin (CAS 25068-38-6) is a chemical substance with GHS signal word Warning; key hazard signal: H315; H319; H317; H411. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for 4,4'-Isopropylidenediphenol/Epichlorohydrin Copolymer →

SOURCE noael studies public
NOAEL studies
3
SOURCE chemical inventory jurisdictions
Regulatory lists
5
SOURCE eu clp annex vi
GHS signal
Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 8 fields
Name
Bisphenol A/ Epichlorohydrin resin
CAS Number
25068-38-6
DTXSID
DTXSID0050479
Synonyms
Phenol, 4,4'-(1-methylethylidene)bis-, polymer withEpidianUP 5-207Araldit LY 556Bisphenol A epichlorohydrin polymer

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Skin Irrit. 2; Eye Irrit. 2; Skin Sens. 1; Aquatic Chronic 2H315; H319; H317; H411GHS07; GHS09Warning

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 60 records
Film formerBinderLubricating agentHardenerChemical reaction regulator

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 5 records
ListKeywordSource
CEDIFDAUnited States Food and Drug Administration (FDA)
Indirect additives food contact (10/2018)FDAUnited States Food and Drug Administration (FDA)
inert_ingredient; non_food_use; PesticidesEPACPCat
CEDIFDAUnited States Food and Drug Administration (FDA)
Indirect additives food contact (10/2018)FDAUnited States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 3 of 3 studies
ValueUnitEndpointRouteSpeciesSource
=60mg/kg bw/dayNOAELoralRabbitToxValDB_ECHA_IUCLID
=180mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
>540mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID

Showing 3 of 3 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane500-033-5ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Frequently Asked Questions

What is the GHS hazard classification for Bisphenol A/ Epichlorohydrin resin?

Bisphenol A/ Epichlorohydrin resin (CAS 25068-38-6) is classified under EU CLP Annex VI as Skin Irrit. 2; Eye Irrit. 2; Skin Sens. 1; Aquatic Chronic 2 with signal word Warning. Hazard statements: H315; H319; H317; H411. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Bisphenol A/ Epichlorohydrin resin?

Bisphenol A/ Epichlorohydrin resin has 3 NOAEL studies in the database. The lowest reported value is 60 mg/kg bw/day via oral in Rabbit. Source: ToxValDB_ECHA_IUCLID.

What regulatory lists include Bisphenol A/ Epichlorohydrin resin?

Bisphenol A/ Epichlorohydrin resin appears on 3 regulatory/inventory lists including CEDI, Indirect additives food contact (10/2018), inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.

Is Bisphenol A/ Epichlorohydrin resin used in cosmetics?

Yes, Bisphenol A/ Epichlorohydrin resin is also indexed as a cosmetic ingredient under the name 4,4'-Isopropylidenediphenol/Epichlorohydrin Copolymer. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Bisphenol A/ Epichlorohydrin resin come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Bisphenol A/ Epichlorohydrin resin used outside industrial chemicals?

Bisphenol A/ Epichlorohydrin resin also appears in cosmetics databases.