What is the NOAEL for N-Undecyl cyanide?
N-Undecyl cyanide has 10 NOAEL studies in the database. The lowest reported value is 14 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
N-Undecyl cyanide
Also known as: Dodecanenitrile, BRN 0970348, 1-Cyanoundecane, Decylacetonitrile, Dodecane nitrile (+8 more)
CAS 2437-25-4
N-Undecyl cyanide (CAS 2437-25-4) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
10
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
19 fields
Name
N-Undecyl cyanide
CAS Number
2437-25-4
DTXSID
DTXSID1022188
Molecular Formula
C12H23N
InChI Key
VXCUURYYWGCLIH-UHFFFAOYSA-N
Monoisotopic Mass
181.18305
Synonyms
DodecanenitrileBRN 09703481-CyanoundecaneDecylacetonitrileDodecane nitrileDodecanonitrileEINECS 219-440-1Lauric acid nitrileLauric nitrileLauronitrileNSC 1804Undecyl cyanide
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =14 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| TL45I6761P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| TL45I6761P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| TL45I6761P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| TL45I6761P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 581 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =250 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =50 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 4 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 10 of 10 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Dodecanenitrile | 219-440-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1879602
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
What regulatory lists include N-Undecyl cyanide?
N-Undecyl cyanide appears on 2 regulatory/inventory lists including IFRA Transparency, consumer_product. Source: EPA CPDat.
Is N-Undecyl cyanide used in cosmetics?
Yes, N-Undecyl cyanide is also indexed as a cosmetic ingredient under the name Dodecanenitrile. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for N-Undecyl cyanide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is N-Undecyl cyanide used outside industrial chemicals?
N-Undecyl cyanide also appears in cosmetics, pharmaceutical databases.