What is the NOAEL for Phenethyl isothiocyanate?
Phenethyl isothiocyanate has 3 NOAEL studies in the database. The lowest reported value is 6U7TFK75KV UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Phenethyl isothiocyanate
Also known as: Benzene, (2-isothiocyanatoethyl)-, 2-Phenylethyl isothiocyanate, Phenylethyl isothiocyanate, 4-12-00-02476, BRN 2084162 (+9 more)
CAS 2257-09-2
Phenethyl isothiocyanate (CAS 2257-09-2) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
3
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
20 fields
Name
Phenethyl isothiocyanate
CAS Number
2257-09-2
DTXSID
DTXSID5021120
Molecular Formula
C9H9NS
InChI Key
IZJDOKYDEWTZSO-UHFFFAOYSA-N
Monoisotopic Mass
163.04557
Synonyms
Benzene, (2-isothiocyanatoethyl)-2-Phenylethyl isothiocyanatePhenylethyl isothiocyanate4-12-00-02476BRN 2084162EINECS 218-855-5NSC 87868Phenylethyl mustard oilUNII-6U7TFK75KV(2-Isothiocyanatoethyl)benzenePEITCPhenylaethylsenfoel
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 3 of 3 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 6U7TFK75KV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6U7TFK75KV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6U7TFK75KV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 3 of 3 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
PHENETHYLISOTHIOCYANATE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
5
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Frequently Asked Questions
What regulatory lists include Phenethyl isothiocyanate?
Phenethyl isothiocyanate appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is Phenethyl isothiocyanate used in cosmetics?
Yes, Phenethyl isothiocyanate is also indexed as a cosmetic ingredient under the name Phenethyl Isothiocyanate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Phenethyl isothiocyanate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Phenethyl isothiocyanate used outside industrial chemicals?
Phenethyl isothiocyanate also appears in cosmetics, pharmaceutical, food safety databases.