Danger GHS06 NOAEL Data REACH Registered Cosmetic Ingredient

2,2-Dimethyl-1,3-propanediyl diacrylate

Also known as: Acrylic acid, 2,2-dimethyl-1,3-propanediol diester, Dimethylolpropane diacrylate, 2,2-Dimethylpropane diacrylate, 2,2-Dimethylpropane-1,3-diol diacrylate, EINECS 218-741-5 (+5 more)

CAS 2223-82-7

2,2-Dimethyl-1,3-propanediyl diacrylate (CAS 2223-82-7) is a chemical substance with GHS signal word Danger; key hazard signal: H311; H315; H319; H317. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.

View cosmetic safety profile for Neopentyl Glycol Dimethacrylate →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Danger

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 16 fields
Name
2,2-Dimethyl-1,3-propanediyl diacrylate
CAS Number
2223-82-7
DTXSID
DTXSID0051869
Molecular Formula
C11H16O4
InChI Key
MXFQRSUWYYSPOC-UHFFFAOYSA-N
Monoisotopic Mass
212.104859
Synonyms
Acrylic acid, 2,2-dimethyl-1,3-propanediol diesterDimethylolpropane diacrylate2,2-Dimethylpropane diacrylate2,2-Dimethylpropane-1,3-diol diacrylateEINECS 218-741-5Neopentyl glycol diacrylateNSC 974071,3-Propanediol, 2,2-dimethyl-, diacrylateViscoat 247UNII-0OHU17DNNU

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Acute Tox. 3 *; Skin Irrit. 2; Eye Irrit. 2; Skin Sens. 1H311; H315; H319; H317GHS06Danger

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE ILO/WHO International Chemical Safety Cards 1 records
FieldValue
Short-term EffectsThe substance is irritating to the eyes, skin and respiratory tract.
Long-term EffectsRepeated or prolonged contact may cause skin sensitization.
Routes of ExposureThe substance can be absorbed into the body by inhalation and through the skin.

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 9 records
Monomers

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
0OHU17DNNUUNIIFDA UNII substance identifier--openFDA substances
0OHU17DNNUUNIIFDA UNII substance identifier--openFDA substances
0OHU17DNNUUNIIFDA UNII substance identifier--openFDA substances
0OHU17DNNUUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered2,2-dimethyl-1,3-propanediyl diacrylate218-741-5ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Frequently Asked Questions

What is the GHS hazard classification for 2,2-Dimethyl-1,3-propanediyl diacrylate?

2,2-Dimethyl-1,3-propanediyl diacrylate (CAS 2223-82-7) is classified under EU CLP Annex VI as Acute Tox. 3 *; Skin Irrit. 2; Eye Irrit. 2; Skin Sens. 1 with signal word Danger. Hazard statements: H311; H315; H319; H317. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for 2,2-Dimethyl-1,3-propanediyl diacrylate?

2,2-Dimethyl-1,3-propanediyl diacrylate has 4 NOAEL studies in the database. The lowest reported value is 0OHU17DNNU UNII. Source: openFDA substances.

Is 2,2-Dimethyl-1,3-propanediyl diacrylate used in cosmetics?

Yes, 2,2-Dimethyl-1,3-propanediyl diacrylate is also indexed as a cosmetic ingredient under the name Neopentyl Glycol Dimethacrylate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2,2-Dimethyl-1,3-propanediyl diacrylate come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does 2,2-Dimethyl-1,3-propanediyl diacrylate have different safety status in cosmetics vs industrial chemicals?

2,2-Dimethyl-1,3-propanediyl diacrylate is classified GHS Danger (H311, H315, H319, H317) in the chemicals database but is allowed in EU cosmetics.

Is 2,2-Dimethyl-1,3-propanediyl diacrylate used outside industrial chemicals?

2,2-Dimethyl-1,3-propanediyl diacrylate also appears in cosmetics databases.