What is the NOAEL for 2-Isobutylthiazole?
2-Isobutylthiazole has 4 NOAEL studies in the database. The lowest reported value is 7N03TDY75D UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2-Isobutylthiazole
Also known as: 2-(2-Methylpropyl)thiazole, Thiazole, 2-(2-methylpropyl)-, EINECS 242-470-1, FEMA No. 3134, NSC 290430 (+2 more)
CAS 18640-74-9
2-Isobutylthiazole (CAS 18640-74-9) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
NOAEL studies
NOAEL studies
4
SOURCE
Chemical inventory jurisdictions
Regulatory lists
4
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
2-Isobutylthiazole
CAS Number
18640-74-9
DTXSID
DTXSID5025653
Molecular Formula
C7H11NS
InChI Key
CMPVUVUNJQERIT-UHFFFAOYSA-N
Monoisotopic Mass
141.061221
Synonyms
2-(2-Methylpropyl)thiazoleThiazole, 2-(2-methylpropyl)-EINECS 242-470-1FEMA No. 3134NSC 290430Thiazole, 2-isobutyl-UNII-7N03TDY75D
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 7N03TDY75D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7N03TDY75D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7N03TDY75D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7N03TDY75D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
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ChEMBL / DailyMed
CHEMBL1870000
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
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Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 2-Isobutylthiazole?
2-Isobutylthiazole appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is 2-Isobutylthiazole used in cosmetics?
Yes, 2-Isobutylthiazole is also indexed as a cosmetic ingredient under the name Isobutylthiazole. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Isobutylthiazole come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Isobutylthiazole used outside industrial chemicals?
2-Isobutylthiazole also appears in cosmetics, pharmaceutical, food safety, cannabis databases.