What is the NOAEL for Nerol oxide?
Nerol oxide has 13 NOAEL studies in the database. The lowest reported value is 20 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.
NOAEL Data
Cosmetic Ingredient
Nerol oxide
Also known as: 5-17-01-00406, BRN 1562957, 3,6-Dihydro-4-methyl-2-(2-methylpropenyl)-2H-pyran, EINECS 217-241-4, FEMA No. 3661 (+3 more)
CAS 1786-08-9
Nerol oxide (CAS 1786-08-9) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
13
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Nerol oxide
CAS Number
1786-08-9
DTXSID
DTXSID6051805
Molecular Formula
C10H16O
InChI Key
FRISMOQHTLZZRP-UHFFFAOYSA-N
Monoisotopic Mass
152.120115
Synonyms
5-17-01-00406BRN 15629573,6-Dihydro-4-methyl-2-(2-methylpropenyl)-2H-pyranEINECS 217-241-4FEMA No. 36612H-Pyran, 3,6-dihydro-4-methyl-2-(2-methylpropenyl)-2H-Pyran, 3,6-dihydro-4-methyl-2-(2-methyl-1-propeyl)-UNII-NSW8112Y7S
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 13 of 13 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 25 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 20 | % | Concentration, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| NSW8112Y7S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NSW8112Y7S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NSW8112Y7S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NSW8112Y7S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 4 | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 6750 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 13500 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 16880 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| =5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 13 of 13 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Nerol oxide?
Nerol oxide appears on 3 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Europe, IFRA Transparency. Source: EPA CPDat.
Is Nerol oxide used in cosmetics?
Yes, Nerol oxide is also indexed as a cosmetic ingredient under the name NEROL OXIDE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Nerol oxide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Nerol oxide used outside industrial chemicals?
Nerol oxide also appears in cosmetics, food safety, cannabis databases.