What is the NOAEL for 3beta-Acetoxy-5-pregnene-20-one?
3beta-Acetoxy-5-pregnene-20-one has 3 NOAEL studies in the database. The lowest reported value is 0G0WWV404B UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
3beta-Acetoxy-5-pregnene-20-one
Also known as: EINECS 217-212-6, UNII-0G0WWV404B, 3beta-Hydroxypregn-5-en-20-one acetate
CAS 1778-02-5
3beta-Acetoxy-5-pregnene-20-one (CAS 1778-02-5) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
Cross-Vertical Regulatory Divergence
3beta-Acetoxy-5-pregnene-20-one is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H332, H351, H361, H362).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
NOAEL studies
NOAEL studies
3
SOURCE
Chemical inventory jurisdictions
Regulatory lists
2
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
3beta-Acetoxy-5-pregnene-20-one
CAS Number
1778-02-5
DTXSID
DTXSID3048942
Molecular Formula
C23H34O3
InChI Key
CRRKVZVYZQXICQ-RJJCNJEVSA-N
Monoisotopic Mass
358.250795
Synonyms
EINECS 217-212-6UNII-0G0WWV404B3beta-Hydroxypregn-5-en-20-one acetate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 3 of 3 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 0G0WWV404B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0G0WWV404B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0G0WWV404B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 3 of 3 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Pregnenolone acetate | 217-212-6 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
CHEMBL1892286
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Frequently Asked Questions
What regulatory lists include 3beta-Acetoxy-5-pregnene-20-one?
3beta-Acetoxy-5-pregnene-20-one appears on 2 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), Canada; pharmaceutical. Source: EPA CPDat.
Is 3beta-Acetoxy-5-pregnene-20-one used in cosmetics?
Yes, 3beta-Acetoxy-5-pregnene-20-one is also indexed as a cosmetic ingredient under the name Pregnenolone Acetate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3beta-Acetoxy-5-pregnene-20-one come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does 3beta-Acetoxy-5-pregnene-20-one have different safety status in cosmetics vs industrial chemicals?
3beta-Acetoxy-5-pregnene-20-one is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H332, H351, H361, H362).
Is 3beta-Acetoxy-5-pregnene-20-one used outside industrial chemicals?
3beta-Acetoxy-5-pregnene-20-one also appears in cosmetics, pharmaceutical databases.