What is the NOAEL for Hexa-2,4-dienyl isobutyrate?
Hexa-2,4-dienyl isobutyrate has 8 NOAEL studies in the database. The lowest reported value is 443XQL39UP UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Hexa-2,4-dienyl isobutyrate
Also known as: 2,4-Hexadienyl isobutyrate, Propanoic acid, 2-methyl-, 2,4-hexadien-1-yl ester, EINECS 240-551-6, 3,5-Hexadienyl isobutyrate, 2,4-Hexadienyl 2-methylpropanoate (+4 more)
CAS 16491-24-0
Hexa-2,4-dienyl isobutyrate (CAS 16491-24-0) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
Hexa-2,4-dienyl isobutyrate
CAS Number
16491-24-0
DTXSID
DTXSID4047414
Molecular Formula
C10H16O2
InChI Key
CVYBRMSQMLJGOI-UHFFFAOYSA-N
Monoisotopic Mass
168.11503
Synonyms
2,4-Hexadienyl isobutyratePropanoic acid, 2-methyl-, 2,4-hexadien-1-yl esterEINECS 240-551-63,5-Hexadienyl isobutyrate2,4-Hexadienyl 2-methylpropanoateIsobutyric acid, 2,4-hexadienyl ester2-Methylpropanoic acid 2,4-hexadienyl esterNSC 195147Sorbyl isobutyrate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 443XQL39UP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 443XQL39UP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 443XQL39UP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 443XQL39UP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include Hexa-2,4-dienyl isobutyrate?
Hexa-2,4-dienyl isobutyrate appears on 2 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is Hexa-2,4-dienyl isobutyrate used in cosmetics?
Yes, Hexa-2,4-dienyl isobutyrate is also indexed as a cosmetic ingredient under the name Hexadienyl Isobutyrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Hexa-2,4-dienyl isobutyrate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Hexa-2,4-dienyl isobutyrate used outside industrial chemicals?
Hexa-2,4-dienyl isobutyrate also appears in cosmetics databases.