NOAEL Data Cosmetic Ingredient

2,5,6-Triaminopyrimidin-4-yl hydrogen sulfate

CAS 1603-02-7

2,5,6-Triaminopyrimidin-4-yl hydrogen sulfate (CAS 1603-02-7) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, SCCS.

View cosmetic safety profile for 2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE →

SOURCE noael studies public
NOAEL studies
50
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
2,5,6-Triaminopyrimidin-4-yl hydrogen sulfate
CAS Number
1603-02-7
DTXSID
DTXSID20862708
Molecular Formula
C4H7N5O4S
InChI Key
DJUGBKWOBAOTFA-UHFFFAOYSA-N
Monoisotopic Mass
221.021875

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Dye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
Europe; Personal care; restrictedEuropean CommissionCosIng

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 50 of 50 studies
ValueUnitEndpointRouteSpeciesSource
200mg/kg bw/day---UnifiedCodex:SCCS_SHADOW:beta.noael_studies
1000mg/kg bw/day--humanUnifiedCodex:SCCS_SHADOW:beta.noael_studies
1000mg/kg bw/day---UnifiedCodex:SCCS_SHADOW:beta.noael_studies
T3YK834X4UUNIIFDA UNII substance identifier--openFDA substances
T3YK834X4UUNIIFDA UNII substance identifier--openFDA substances
T3YK834X4UUNIIFDA UNII substance identifier--openFDA substances
T3YK834X4UUNIIFDA UNII substance identifier--openFDA substances
50mg/kg bw/dayLOAELoralratCOSMOS_DB
=0.83mg/kg bw/dNOAELoralratSCCS_vision_codex
=0.83mg/kg bw/dNOAELoralratSCCS_vision_codex
=0.83mg/kg bw/dNOAELoralratSCCS_vision_codex
=0.83mg/kg bw/dNOAELoralratSCCS_vision_codex
=100mg/kg bw/dNOAELoralratSCCS_vision_codex
=100mg/kg bw/dNOAELoralratSCCS_vision_codex
=100mg/kg bw/dNOAELoralratSCCS_vision_codex
=100mg/kg bw/dNOAELoralratSCCS_vision_codex
=200mg/kg bw/dayNOAELoralratSCCS_vision_codex
=200mg/kg bw/dNOAELoralratSCCS_vision_codex
=200mg/kg bwNOAELoralratSCCNFP_vision_codex
=200mg/kg bw/dayNOAELoralratSCCS_vision_codex
=200mg/kg bw/dayNOAELoralratSCCS_vision_codex
=200mg/kg bw/dNOAELoralratSCCS_vision_codex
=200mg/kg bw/dNOAELoralratSCCS_vision_codex
=200mg/kg bwNOAELoralratSCCNFP_vision_codex
=200mg/kg bwNOAELoralratSCCNFP_vision_codex
=200mg/kg bw/dayNOAELoralratSCCS_vision_codex
=200mg/kg bw/dNOAELoralratSCCS_vision_codex
=200mg/kg bwNOAELoralratSCCNFP_vision_codex
=1000mg/kg bw/dayNOAEL-humanSCCS_vision_codex
=1000mg/kg bwNOAEL-ratSCCNFP_vision_codex
=1000mg/kg bw/dayNOAEL-humanSCCS_vision_codex
=1000mg/kg bw/dayNOAEL-humanSCCS_vision_codex
=1000mg/kg bwNOAEL-ratSCCNFP_vision_codex
=1000mg/kg bwNOAEL-ratSCCNFP_vision_codex
=1000mg/kg bw/dayNOAEL-humanSCCS_vision_codex
=1000mg/kg bwNOAEL-ratSCCNFP_vision_codex
=0.83mg/kg bw/ddermal absorptionoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
=100mg/kg bw/ddermal absorptionoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
=200mg/kg bw/ddermal absorptionoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
1000mg/kg bwdermal absorption-ratUnifiedCodex:SCCNFP:beta.noael_studies
200mg/kg bw/daygenotoxicity--UnifiedCodex:SCCS_SHADOW:beta.noael_studies
200mg/kg bw/daygenotoxicity--UnifiedCodex:SCCS_SHADOW:beta.noael_studies
200mg/kg bwrepeated dose toxicityoralratUnifiedCodex:SCCNFP:beta.noael_studies
200mg/kg bwrepeated dose toxicitydermalrabbitUnifiedCodex:SCCNFP:beta.noael_studies
200mg/kg bwrepeated dose toxicityoralratUnifiedCodex:SCCNFP:beta.noael_studies
200mg/kg bwrepeated dose toxicityoralratUnifiedCodex:SCCNFP:beta.noael_studies
200mg/kg bw/dayrepeated dose toxicityoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
200mg/kg bw/dayrepeated dose toxicityoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
200mg/kg bw/dayrepeated dose toxicityoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
200mg/kg bw/dayrepeated dose toxicityoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies

Showing 50 of 50 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.

SCCS Opinions

EU Scientific Committee opinions tied to the matched substance.

SOURCE EU SCCS 2 opinions
OpinionDateConclusionMax Conc.Concerns
SCCS/1561/1525 June 2015safe0.5%sensitisation potential not excluded
SCCP/1168/0830 September 2008safe0.5%sensitisation potential not excluded

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
III/301
Category
Hair Dyes
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for 2,5,6-Triaminopyrimidin-4-yl hydrogen sulfate?

2,5,6-Triaminopyrimidin-4-yl hydrogen sulfate has 50 NOAEL studies in the database. The lowest reported value is 200 mg/kg bw/day. Source: UnifiedCodex:SCCS_SHADOW:beta.noael_studies.

What regulatory lists include 2,5,6-Triaminopyrimidin-4-yl hydrogen sulfate?

2,5,6-Triaminopyrimidin-4-yl hydrogen sulfate appears on 1 regulatory/inventory list including Europe; Personal care; restricted. Source: EPA CPDat.

Is 2,5,6-Triaminopyrimidin-4-yl hydrogen sulfate used in cosmetics?

Yes, 2,5,6-Triaminopyrimidin-4-yl hydrogen sulfate is also indexed as a cosmetic ingredient under the name 2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2,5,6-Triaminopyrimidin-4-yl hydrogen sulfate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 2,5,6-Triaminopyrimidin-4-yl hydrogen sulfate used outside industrial chemicals?

2,5,6-Triaminopyrimidin-4-yl hydrogen sulfate also appears in cosmetics databases.