What is the NOAEL for Dimethylbenzylcarbinyl acetate?
Dimethylbenzylcarbinyl acetate has 14 NOAEL studies in the database. The lowest reported value is 12.695 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Dimethylbenzylcarbinyl acetate
Also known as: alpha,alpha-Dimethylphenethyl acetate, Benzeneethanol, .alpha.,.alpha.-dimethyl-, 1-acetate, Benzeneethanol, alpha,alpha-dimethyl-, 1-acetate, Benzyl dimethyl carbinyl acetate, Benzyldimethyl carbinyl acetate (+11 more)
CAS 151-05-3
Dimethylbenzylcarbinyl acetate (CAS 151-05-3) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Dimethylbenzyl Carbinyl Acetate (DMBCA) →
SOURCE
noael studies public
NOAEL studies
14
SOURCE
chemical inventory jurisdictions
Regulatory lists
6
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
22 fields
Name
Dimethylbenzylcarbinyl acetate
CAS Number
151-05-3
DTXSID
DTXSID3041877
Molecular Formula
C12H16O2
InChI Key
FLUWAIIVLCVEKF-UHFFFAOYSA-N
Monoisotopic Mass
192.11503
Synonyms
alpha,alpha-Dimethylphenethyl acetateBenzeneethanol, .alpha.,.alpha.-dimethyl-, 1-acetateBenzeneethanol, alpha,alpha-dimethyl-, 1-acetateBenzyl dimethyl carbinyl acetateBenzyldimethyl carbinyl acetateBenzyldimethylcarbinol acetateBenzyldimethylcarbinyl acetate2-Benzyl-2-propyl acetateBRN 1941670alpha,alpha-Dimethylbenzeneethyl acetateDimethylbenzyl carbinol acetateDimethylbenzylcarbinol acetate
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
60 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 14 of 14 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =12.695 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 6Y9488RL8H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6Y9488RL8H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6Y9488RL8H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6Y9488RL8H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 775 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =3300 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =360 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| ~500 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 14 of 14 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
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ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | α,α-dimethylphenethyl acetate | 205-781-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
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EMBL-EBI ChEMBL
CHEMBL3561182
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
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Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Dimethylbenzylcarbinyl acetate?
Dimethylbenzylcarbinyl acetate appears on 6 regulatory/inventory lists including Europe, IFRA Transparency, consumer_product, and 3 more. Source: EPA CPDat.
Is Dimethylbenzylcarbinyl acetate used in cosmetics?
Yes, Dimethylbenzylcarbinyl acetate is also indexed as a cosmetic ingredient under the name Dimethylbenzyl Carbinyl Acetate (DMBCA). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Dimethylbenzylcarbinyl acetate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Dimethylbenzylcarbinyl acetate used outside industrial chemicals?
Dimethylbenzylcarbinyl acetate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.