What is the NOAEL for Disodium succinate?
Disodium succinate has 9 NOAEL studies in the database. The lowest reported value is 41.1 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Disodium succinate
Also known as: Butanedioic acid, sodium salt (1:2), Butanedioic acid, disodium salt, Succinic acid, disodium salt, SS50, SUCCINATE, DISODIUM (+12 more)
CAS 150-90-3
Disodium succinate (CAS 150-90-3) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
9
SOURCE
Chemical inventory jurisdictions
Regulatory lists
3
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
23 fields
Name
Disodium succinate
CAS Number
150-90-3
DTXSID
DTXSID5059741
Molecular Formula
C4H6O4.2Na
InChI Key
ZDQYSKICYIVCPN-UHFFFAOYSA-L
Monoisotopic Mass
164.006147
Synonyms
Butanedioic acid, sodium salt (1:2)Butanedioic acid, disodium saltSuccinic acid, disodium saltSS50SUCCINATE, DISODIUMBUTANDIOIC ACID, DISODIUM SALTEINECS 205-778-7FEMA No. 3277SoduxinJantaran sodnyUNII-V8ZGC8ISR3Succinic acid disodium salt
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
10 records
Surfactant (surface active agent)DeodorizerFragranceNo specific technical functionFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =41.1 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| V8ZGC8ISR3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V8ZGC8ISR3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V8ZGC8ISR3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V8ZGC8ISR3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =100 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| 180 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| =300 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| 500 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
Showing 9 of 9 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Disodium succinate | 205-778-7 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
CHEMBL3907604
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Disodium succinate?
Disodium succinate appears on 3 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Europe. Source: EPA CPDat.
Is Disodium succinate used in cosmetics?
Yes, Disodium succinate is also indexed as a cosmetic ingredient under the name Disodium Succinate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Disodium succinate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Disodium succinate used outside industrial chemicals?
Disodium succinate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.