What is the NOAEL for Hexyl acetate?
Hexyl acetate has 12 NOAEL studies in the database. The lowest reported value is 48 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Hexyl acetate
Also known as: 4-02-00-00159, BRN 1747138, EINECS 205-572-7, FEMA No. 2565, l-Hexyl acetate (+2 more)
CAS 142-92-7
Hexyl acetate (CAS 142-92-7) is a chemical substance. Key regulatory status: REACH registered, 9 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
12
SOURCE
chemical inventory jurisdictions
Regulatory lists
9
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Hexyl acetate
CAS Number
142-92-7
DTXSID
DTXSID6022006
Molecular Formula
C8H16O2
InChI Key
AOGQPLXWSUTHQB-UHFFFAOYSA-N
Monoisotopic Mass
144.11503
Synonyms
4-02-00-00159BRN 1747138EINECS 205-572-7FEMA No. 2565l-Hexyl acetateHexylester kyseliny octoveUNII-7U7KU3MWT0
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
FragranceDeodorizerFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
9 records
| List | Keyword | Source |
|---|---|---|
| air; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| air; Cleaning products and household care - air freshener; detected; emissions | Elsevier | CPCat |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| consumer_product | P&G | Proctor & Gamble |
| air; Cleaning products and household care - air freshener; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 12 of 12 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =48 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 7U7KU3MWT0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7U7KU3MWT0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7U7KU3MWT0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7U7KU3MWT0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =42000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =900 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =900 | mg/kg bw/day | NOAEL | oral: gavage | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =900 | mg/kg bw/day | NOAEL | oral: gavage | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 12 of 12 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Hexyl acetate | 205-572-7 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Other
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
HEXYL ACETATE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Hexyl acetate?
Hexyl acetate appears on 8 regulatory/inventory lists including air; detected; emissions; Europe; Toys and children's products, air; Cleaning products and household care - air freshener; detected; emissions, IFRA Transparency, and 5 more. Source: EPA CPDat.
Is Hexyl acetate used in cosmetics?
Yes, Hexyl acetate is also indexed as a cosmetic ingredient under the name Hexyl Acetate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Hexyl acetate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Hexyl acetate used outside industrial chemicals?
Hexyl acetate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.