What is the NOAEL for Coenzyme B12?
Coenzyme B12 has 4 NOAEL studies in the database. The lowest reported value is F0R1QK73KB UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Coenzyme B12
Also known as: BRN 4122932, Cobalamine coenzyme, EINECS 237-627-6, Cobamamidum, 5,6-Dimethylbenzimidazolylcobamid coenzym (+1 more)
CAS 13870-90-1
Coenzyme B12 (CAS 13870-90-1) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Coenzyme B12
CAS Number
13870-90-1
DTXSID
DTXSID1046009
Molecular Formula
C62H90N13O14P.C10H12N5O3.Co
InChI Key
ZIHHMGTYZOSFRC-CXGXMSGESA-L
Monoisotopic Mass
1580.67399
Synonyms
BRN 4122932Cobalamine coenzymeEINECS 237-627-6Cobamamidum5,6-Dimethylbenzimidazolylcobamid coenzymUNII-F0R1QK73KB
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
AntioxidantHumectantSoftener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| pharmaceutical | US International Trade Commission | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| F0R1QK73KB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F0R1QK73KB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F0R1QK73KB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F0R1QK73KB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
cobamamide
ChEMBL Phase
Not listed
Adverse Events
1639
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Coenzyme B12?
Coenzyme B12 appears on 3 regulatory/inventory lists including pharmaceutical, Canada; pharmaceutical, Canada; consumer_product; Substances in Products - Canada (4/2014). Source: EPA CPDat.
Is Coenzyme B12 used in cosmetics?
Yes, Coenzyme B12 is also indexed as a cosmetic ingredient under the name Cobamamide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Coenzyme B12 come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Coenzyme B12 used outside industrial chemicals?
Coenzyme B12 also appears in cosmetics, pharmaceutical, cannabis databases.