NOAEL Data Cosmetic Ingredient

Mafenide hydrochloride

Also known as: Ambamide hydrochloride, p-(Aminomethyl)benzenesulfonamide hydrochloride, 4-Aminomethylbenzenesulfonamide hydrochloride, p-(Aminomethyl)benzenesulfonamide monohydrochloride, p-Aminomethylphenylsulfonamide hydrochloride (+15 more)

CAS 138-37-4

Mafenide hydrochloride (CAS 138-37-4) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Mafenide HCl →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 26 fields
Name
Mafenide hydrochloride
CAS Number
138-37-4
DTXSID
DTXSID6045296
Molecular Formula
C7H10N2O2S.ClH
InChI Key
SIACJRVYIPXFKS-UHFFFAOYSA-N
Monoisotopic Mass
222.022976
Synonyms
Ambamide hydrochloridep-(Aminomethyl)benzenesulfonamide hydrochloride4-Aminomethylbenzenesulfonamide hydrochloridep-(Aminomethyl)benzenesulfonamide monohydrochloridep-Aminomethylphenylsulfonamide hydrochloridealpha-Amino-p-toluenesulfonamide hydrochlorideEINECS 205-325-3Emilene hydrochlorideHomosulfamineHomosulfamine hydrochlorideHomosulfanilamide hydrochloride4-Homosulfanilamide hydrochloride

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Biocide

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
active_ingredient; AustraliaAustralian Pesticides and Veterinary Medicines AuthorityCPCat
active_ingredient; AustraliaAustralian Pesticides and Veterinary Medicines AuthorityCPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
3J751V0284UNIIFDA UNII substance identifier--openFDA substances
3J751V0284UNIIFDA UNII substance identifier--openFDA substances
3J751V0284UNIIFDA UNII substance identifier--openFDA substances
3J751V0284UNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL MAFENIDE HYDROCHLORIDE
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
4
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Mafenide hydrochloride?

Mafenide hydrochloride has 4 NOAEL studies in the database. The lowest reported value is 3J751V0284 UNII. Source: openFDA substances.

What regulatory lists include Mafenide hydrochloride?

Mafenide hydrochloride appears on 1 regulatory/inventory list including active_ingredient; Australia. Source: EPA CPDat.

Is Mafenide hydrochloride used in cosmetics?

Yes, Mafenide hydrochloride is also indexed as a cosmetic ingredient under the name Mafenide HCl. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Mafenide hydrochloride come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Mafenide hydrochloride used outside industrial chemicals?

Mafenide hydrochloride also appears in cosmetics, pharmaceutical databases.