What is the NOAEL for 1,2,4-Benzenetriamine, N'-phenyl-?
1,2,4-Benzenetriamine, N'-phenyl- has 4 NOAEL studies in the database. The lowest reported value is 45DN363J8C UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
1,2,4-Benzenetriamine, N'-phenyl-
Also known as: 3-13-00-00552, BRN 1964383, Diphenylamine, 2,4-diamino-, NSC 401132, N(sup 1)-Phenyl-1,2,4-benzenetriamine (+2 more)
CAS 136-17-4
1,2,4-Benzenetriamine, N'-phenyl- (CAS 136-17-4) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
Cross-Vertical Regulatory Divergence
1,2,4-Benzenetriamine, N'-phenyl- is prohibited in EU cosmetics but has active industrial GHS classifications (H301, H311, H331, H319, H373, H400, H410).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
1,2,4-Benzenetriamine, N'-phenyl-
CAS Number
136-17-4
DTXSID
DTXSID10159619
Molecular Formula
C12H13N3
InChI Key
VOSLIUIVGWBSOK-UHFFFAOYSA-N
Monoisotopic Mass
199.110947
Synonyms
3-13-00-00552BRN 1964383Diphenylamine, 2,4-diamino-NSC 401132N(sup 1)-Phenyl-1,2,4-benzenetriamineUNII-45DN363J8C2,4-Diaminodiphenylamine
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Dye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| banned; Europe; Personal care | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 45DN363J8C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 45DN363J8C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 45DN363J8C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 45DN363J8C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1241074
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 1,2,4-Benzenetriamine, N'-phenyl-?
1,2,4-Benzenetriamine, N'-phenyl- appears on 1 regulatory/inventory list including banned; Europe; Personal care. Source: EPA CPDat.
Is 1,2,4-Benzenetriamine, N'-phenyl- used in cosmetics?
Yes, 1,2,4-Benzenetriamine, N'-phenyl- is also indexed as a cosmetic ingredient under the name 2,4-Diaminodiphenylamine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1,2,4-Benzenetriamine, N'-phenyl- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does 1,2,4-Benzenetriamine, N'-phenyl- have different safety status in cosmetics vs industrial chemicals?
1,2,4-Benzenetriamine, N'-phenyl- is prohibited in EU cosmetics but has active industrial GHS classifications (H301, H311, H331, H319, H373, H400, H410).
Is 1,2,4-Benzenetriamine, N'-phenyl- used outside industrial chemicals?
1,2,4-Benzenetriamine, N'-phenyl- also appears in cosmetics, pharmaceutical databases.