What is the NOAEL for 3,5-Dimethyl-1,2-cyclopentanedione?
3,5-Dimethyl-1,2-cyclopentanedione has 7 NOAEL studies in the database. The lowest reported value is DV18V4XD6W UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
3,5-Dimethyl-1,2-cyclopentanedione
Also known as: 1,2-Cyclopentanedione, 3,5-dimethyl-, CYCLOPENTA-1,2-DIONE, 3,5-DIMETHYL-, 3,5-Dimethylcyclopentane-1,2-dione, EC No.: 236-811-3, EINECS 236-811-3 (+2 more)
CAS 13494-07-0
3,5-Dimethyl-1,2-cyclopentanedione (CAS 13494-07-0) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for 3,4-Dimethylcyclopentane-1,2-Dione →
SOURCE
NOAEL studies
NOAEL studies
7
SOURCE
Chemical inventory jurisdictions
Regulatory lists
3
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
3,5-Dimethyl-1,2-cyclopentanedione
CAS Number
13494-07-0
DTXSID
DTXSID0047660
Molecular Formula
C7H10O2
InChI Key
MIDXCONKKJTLDX-UHFFFAOYSA-N
Monoisotopic Mass
126.06808
Synonyms
1,2-Cyclopentanedione, 3,5-dimethyl-CYCLOPENTA-1,2-DIONE, 3,5-DIMETHYL-3,5-Dimethylcyclopentane-1,2-dioneEC No.: 236-811-3EINECS 236-811-3FEMA No. 3269UNII-DV18V4XD6W
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Flavouring and nutrientFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| DV18V4XD6W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DV18V4XD6W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DV18V4XD6W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DV18V4XD6W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =200 | mg/kg bw/day | NOAEL | oral | Rat | EFSA |
| =200 | mg/kg bw/day | NOAEL | - | Rat | EFSA |
| 500 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
Showing 7 of 7 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 3,5-Dimethyl-1,2-cyclopentanedione?
3,5-Dimethyl-1,2-cyclopentanedione appears on 3 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Europe. Source: EPA CPDat.
Is 3,5-Dimethyl-1,2-cyclopentanedione used in cosmetics?
Yes, 3,5-Dimethyl-1,2-cyclopentanedione is also indexed as a cosmetic ingredient under the name 3,4-Dimethylcyclopentane-1,2-Dione. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3,5-Dimethyl-1,2-cyclopentanedione come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 3,5-Dimethyl-1,2-cyclopentanedione used outside industrial chemicals?
3,5-Dimethyl-1,2-cyclopentanedione also appears in cosmetics, food safety, cannabis databases.