NOAEL Data Cosmetic Ingredient

Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1)

CAS 130-40-5

Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1) (CAS 130-40-5) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Sodium Riboflavin Phosphate →

SOURCE noael studies public
NOAEL studies
8
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 5 fields
Name
Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1)
CAS Number
130-40-5
DTXSID
DTXSID80889330
Molecular Formula
C17H21N4O9P.Na
InChI Key
OHSHFZJLPYLRIP-BMZHGHOISA-M

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records
Softener and conditionerFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 8 of 8 studies
ValueUnitEndpointRouteSpeciesSource
<=0.5mg/kg bw/dayADI (group)-ConsumersEFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx
<=0.5mg/kg bw/dayADI (group)-ConsumersEFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx
957E53WV42UNIIFDA UNII substance identifier--openFDA substances
957E53WV42UNIIFDA UNII substance identifier--openFDA substances
957E53WV42UNIIFDA UNII substance identifier--openFDA substances
957E53WV42UNIIFDA UNII substance identifier--openFDA substances
=160mg/kg bw/dayNOAELoralRatToxValDB_EFSA
=160mg/kg bw/dayNOAEL-RatEFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx

Showing 8 of 8 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL RIBOFLAVIN 5'-PHOSPHATE
ChEMBL Phase
4
Adverse Events
446
Bioactivity
3
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

E101a — ADI: 0.5 mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1)?

Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1) has 8 NOAEL studies in the database. The lowest reported value is 0.5 mg/kg bw/day in Consumers. Source: EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx.

What regulatory lists include Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1)?

Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1) appears on 1 regulatory/inventory list including food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.

Is Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1) used in cosmetics?

Yes, Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1) is also indexed as a cosmetic ingredient under the name Sodium Riboflavin Phosphate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1) come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1) used outside industrial chemicals?

Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1) also appears in cosmetics, pharmaceutical, food safety, cannabis databases.