What is the NOAEL for Sodium acetate?
Sodium acetate has 16 NOAEL studies in the database. The lowest reported value is 1057.9 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Sodium acetate
Also known as: Caswell No. 741A, EINECS 204-823-8, EPA Pesticide Chemical Code 044006, FEMA No. 3024, FEMA Number 3024 (+8 more)
CAS 127-09-3
Sodium acetate (CAS 127-09-3) is a chemical substance. Key regulatory status: REACH registered, 13 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
SOURCE
noael studies public
NOAEL studies
16
SOURCE
chemical inventory jurisdictions
Regulatory lists
13
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
Sodium acetate
CAS Number
127-09-3
DTXSID
DTXSID2027044
Molecular Formula
C2H4O2.Na
InChI Key
VMHLLURERBWHNL-UHFFFAOYSA-M
Synonyms
Caswell No. 741AEINECS 204-823-8EPA Pesticide Chemical Code 044006FEMA No. 3024FEMA Number 3024Natrium aceticumNSC 77459Sodii acetasSodium ethanoateOctan sodnyUNII-NVG71ZZ7P0Natriumazetat
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| GHS Signal Word | WARNING |
| GHS Hazard Statements | Causes eye irritation |
| Short-term Effects | The substance is mildly irritating to the eyes and skin. |
| Routes of Exposure | The substance can be absorbed into the body by ingestion. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
50 records
pH regulating agentDeodorizerDegradant/impurityFragranceFlame retardantPigmentAnti-static agentFlavouring and nutrientPharmaceuticalSurfactant (surface active agent)Processing aids not otherwise specifiedBiocide
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
13 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| animal_products | USDA | United States Department of Agriculture (USDA) |
| Europe; plastic_additive | European Chemicals Agency | European Chemicals Agency (ECHA) |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Cleaning products and household care - laundry and fabric treatment - laundry detergent; Europe | Danish EPA | Danish EPA |
| fracking; water | NY Department of Conservation | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 16 of 16 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =1057.9 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| NVG71ZZ7P0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NVG71ZZ7P0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NVG71ZZ7P0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NVG71ZZ7P0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >30 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| =1943 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =2700 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =3160 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =3500 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =3530 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| <4640 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 21 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =50 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 102 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| >=3600 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 16 of 16 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Sodium acetate | 204-823-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Other
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
SODIUM ACETATE
ChEMBL Phase
4
Adverse Events
14
Bioactivity
3
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E262 — ADI: NOT LIMITED mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Sodium acetate?
Sodium acetate appears on 11 regulatory/inventory lists including inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, active_ingredient; Europe; Pesticides, and 8 more. Source: EPA CPDat.
Is Sodium acetate used in cosmetics?
Yes, Sodium acetate is also indexed as a cosmetic ingredient under the name Sodium Acetate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium acetate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Sodium acetate used outside industrial chemicals?
Sodium acetate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.