NOAEL Data Cosmetic Ingredient

Saccharose acetate isobutyrate

Also known as: Isobutyric acid, hexaester with sucrose diacetate, Sucrose, diacetate hexaisobutyrate, Sucrose acetate isobutanoate, (2R,3R,4S,5R,6R)-2-((Acetyloxy)methyl)-6-(((2S,3S,4R,5R)-5-((acetyloxy)methyl)-3,4-bis((2-methylpropanoyl)oxy)-2-(((2-methylpropanoyl)oxy)methyl)tetrahydrofuran-2-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl tris(2-methylpropanoate), α-D-Glucopyranoside, 6-O-acetyl-1,3,4-tris-O-(2-methyl-1-oxopropyl)-β-D-fructofuranosyl, 6-acetate 2,3,4-tris(2-methylpropanoate) (+12 more)

CAS 126-13-6

Saccharose acetate isobutyrate (CAS 126-13-6) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Sucrose Acetate Isobutyrate →

SOURCE noael studies public
NOAEL studies
29
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 23 fields
Name
Saccharose acetate isobutyrate
CAS Number
126-13-6
DTXSID
DTXSID3027035
Molecular Formula
C40H62O19
InChI Key
ZNEBZIJCDDCNRC-SWTLDUCYSA-N
Monoisotopic Mass
846.38853
Synonyms
Isobutyric acid, hexaester with sucrose diacetateSucrose, diacetate hexaisobutyrateSucrose acetate isobutanoate(2R,3R,4S,5R,6R)-2-((Acetyloxy)methyl)-6-(((2S,3S,4R,5R)-5-((acetyloxy)methyl)-3,4-bis((2-methylpropanoyl)oxy)-2-(((2-methylpropanoyl)oxy)methyl)tetrahydrofuran-2-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl tris(2-methylpropanoate)α-D-Glucopyranoside, 6-O-acetyl-1,3,4-tris-O-(2-methyl-1-oxopropyl)-β-D-fructofuranosyl, 6-acetate 2,3,4-tris(2-methylpropanoate)SUCROSE ACETATE ISOBUTYRATESucrose acetoisobutyrateEINECS 204-771-6UNII-H5KI1C3YTVBinester SAABSAIBE 444

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 7 records
Film formerPlasticizerSolventFlavouring and nutrientProcessing aids not otherwise specifiedSurface modifier

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 29 of 29 studies
ValueUnitEndpointRouteSpeciesSource
=20mg/kg bw/dayADI-ConsumersEFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx
=20mg/kg bw/dayADI-ConsumersEFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx
H5KI1C3YTVUNIIFDA UNII substance identifier--openFDA substances
H5KI1C3YTVUNIIFDA UNII substance identifier--openFDA substances
H5KI1C3YTVUNIIFDA UNII substance identifier--openFDA substances
H5KI1C3YTVUNIIFDA UNII substance identifier--openFDA substances
>5000mg/kg bwLD50oralRatNTP_ICE_acute_oral
450mg/kg bw/dayLOAELoraldogCOSMOS_DB
500mg/kg bw/dayLOAELoralratCOSMOS_DB
150mg/kg bw/dayNOAELoraldogCOSMOS_DB
190mg/kg bw/dayNOAELoralratCOSMOS_DB
375mg/kg bw/dayNOAELoraldogCOSMOS_DB
450mg/kg bw/dayNOAELoraldogCOSMOS_DB
1200mg/kg bw/dayNOAELoralrabbitCOSMOS_DB
1290mg/kg bw/dayNOAELoraldogCOSMOS_DB
2000mg/kg bw/dayNOAELoralratCOSMOS_DB
=2000mg/kg bw/dayNOAELoralRatToxValDB_EFSA
=2000mg/kg bw/dayNOAELoral: feedRatEFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx
2226mg/kg bw/dayNOAELoralratCOSMOS_DB
2247mg/kg bw/dayNOAELoralratCOSMOS_DB
2400mg/kg bw/dayNOAELoralmonkeyCOSMOS_DB
2500mg/kg bw/dayNOAELoralratCOSMOS_DB
2592mg/kg bw/dayNOAELoralratCOSMOS_DB
2707mg/kg bw/dayNOAELoralratCOSMOS_DB
4690mg/kg bw/dayNOAELoralratCOSMOS_DB
5000mg/kg bw/dayNOAELoralratCOSMOS_DB
5300mg/kg bw/dayNOAELoralratCOSMOS_DB
5800mg/kg bw/dayNOAELoralmouseCOSMOS_DB
10000mg/kg bw/dayNOAELoralmonkeyCOSMOS_DB

Showing 29 of 29 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Rheology Modifier
View full cosmetic safety profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 2 records

E444 — ADI: 20 mg/kg bw | FDA GRAS: FDA has no questions

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Saccharose acetate isobutyrate?

Saccharose acetate isobutyrate has 29 NOAEL studies in the database. The lowest reported value is 20 mg/kg bw/day in Consumers. Source: EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx.

What regulatory lists include Saccharose acetate isobutyrate?

Saccharose acetate isobutyrate appears on 1 regulatory/inventory list including food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.

Is Saccharose acetate isobutyrate used in cosmetics?

Yes, Saccharose acetate isobutyrate is also indexed as a cosmetic ingredient under the name Sucrose Acetate Isobutyrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Saccharose acetate isobutyrate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Saccharose acetate isobutyrate used outside industrial chemicals?

Saccharose acetate isobutyrate also appears in cosmetics, food safety, cannabis databases.