What is the NOAEL for Propanoic acid, 3,3'-thiobis-, didodecyl ester?
Propanoic acid, 3,3'-thiobis-, didodecyl ester has 7 NOAEL studies in the database. The lowest reported value is 3 mg/kg via oral in Human. Source: ToxValDB_WHO_JECFA_ADI.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Propanoic acid, 3,3'-thiobis-, didodecyl ester
Also known as: 4-03-00-00744, BRN 1808848, Dilauryl thiodipropionic acid, EINECS 204-614-1, 3,3'-Thiobispropionic acid, didodecyl ester (+3 more)
CAS 123-28-4
Propanoic acid, 3,3'-thiobis-, didodecyl ester (CAS 123-28-4) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Dilauryl Thiodipropionate →
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Propanoic acid, 3,3'-thiobis-, didodecyl ester
CAS Number
123-28-4
DTXSID
DTXSID2026999
Molecular Formula
C30H58O4S
InChI Key
GHKOFFNLGXMVNJ-UHFFFAOYSA-N
Monoisotopic Mass
514.405582
Synonyms
4-03-00-00744BRN 1808848Dilauryl thiodipropionic acidEINECS 204-614-13,3'-Thiobispropionic acid, didodecyl esterThiodipropionic acid, dilauryl esterDilaurylester kyseliny beta',beta'-thiodipropionoveUNII-V51YH1B080
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
30 records
PreservativeAntioxidantFragranceHeat stabilizerPlasticizerUV stabilizer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| <=3 | mg/kg | ADI | oral | Human | ToxValDB_WHO_JECFA_ADI |
| =24.7 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| V51YH1B080 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V51YH1B080 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V51YH1B080 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V51YH1B080 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =350 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HPVIS |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Didodecyl 3,3'-thiodipropionate | 204-614-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Frequently Asked Questions
What regulatory lists include Propanoic acid, 3,3'-thiobis-, didodecyl ester?
Propanoic acid, 3,3'-thiobis-, didodecyl ester appears on 3 regulatory/inventory lists including drinking_water; Europe; manufacturing; plastic_additive, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), IFRA Transparency. Source: EPA CPDat.
Is Propanoic acid, 3,3'-thiobis-, didodecyl ester used in cosmetics?
Yes, Propanoic acid, 3,3'-thiobis-, didodecyl ester is also indexed as a cosmetic ingredient under the name Dilauryl Thiodipropionate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Propanoic acid, 3,3'-thiobis-, didodecyl ester come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Propanoic acid, 3,3'-thiobis-, didodecyl ester used outside industrial chemicals?
Propanoic acid, 3,3'-thiobis-, didodecyl ester also appears in cosmetics databases.