What is the NOAEL for Tetrahydrobisdemethoxydiferuloylmethane?
Tetrahydrobisdemethoxydiferuloylmethane has 6 NOAEL studies in the database. The lowest reported value is 973IBV8W7I UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Tetrahydrobisdemethoxydiferuloylmethane
Also known as: UNII-973IBV8W7I, 1,7-Bis(4-hydroxyphenyl)-heptane-3,5-dione, 3,5-Heptanedione, 1,7-bis(4-hydroxyphenyl)-, Bisdemethoxytetrahydrocurcumin, Tetrahydrobisdemethoxycurcumin (+1 more)
CAS 113482-94-3
Tetrahydrobisdemethoxydiferuloylmethane (CAS 113482-94-3) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
View cosmetic safety profile for Tetrahydrobisdemethoxydiferuloylmethane →
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Tetrahydrobisdemethoxydiferuloylmethane
CAS Number
113482-94-3
DTXSID
DTXSID60150419
Molecular Formula
C19H20O4
InChI Key
KTRRXJQAOOYSDA-UHFFFAOYSA-N
Monoisotopic Mass
312.136159
Synonyms
UNII-973IBV8W7I1,7-Bis(4-hydroxyphenyl)-heptane-3,5-dione3,5-Heptanedione, 1,7-bis(4-hydroxyphenyl)-BisdemethoxytetrahydrocurcuminTetrahydrobisdemethoxycurcuminLetestuianin C
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
8 records
AntioxidantSoftener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 973IBV8W7I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 973IBV8W7I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 973IBV8W7I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 973IBV8W7I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =200 | mg/kg bw/day | NOAEL | oral: gavage | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =400 | mg/kg bw/day | NOAEL | oral: gavage | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
Showing 6 of 6 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
LETESTUIANIN C
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
3
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
Is Tetrahydrobisdemethoxydiferuloylmethane used in cosmetics?
Yes, Tetrahydrobisdemethoxydiferuloylmethane is also indexed as a cosmetic ingredient under the name Tetrahydrobisdemethoxydiferuloylmethane. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Tetrahydrobisdemethoxydiferuloylmethane come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Tetrahydrobisdemethoxydiferuloylmethane used outside industrial chemicals?
Tetrahydrobisdemethoxydiferuloylmethane also appears in cosmetics, pharmaceutical, cannabis databases.