What is the NOAEL for Dodecyltrimethylammonium bromide?
Dodecyltrimethylammonium bromide has 24 NOAEL studies in the database. The lowest reported value is 10 mg/kg/d via dermal in mouse. Source: UnifiedCodex:CIR:beta.noael_studies.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Dodecyltrimethylammonium bromide
Also known as: EINECS 214-290-3, UNII-6IC8NZ97S2, DDTMABr, DTAB, Dctab (+4 more)
CAS 1119-94-4
Dodecyltrimethylammonium bromide (CAS 1119-94-4) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Dodecyltrimethylammonium bromide is classified GHS Danger (H301, H302, H315, H317, H319, H335, H400, H410) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
24
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
Dodecyltrimethylammonium bromide
CAS Number
1119-94-4
DTXSID
DTXSID5044366
Molecular Formula
C15H34N.BrH
InChI Key
XJWSAJYUBXQQDR-UHFFFAOYSA-M
Monoisotopic Mass
308.195288
Synonyms
EINECS 214-290-3UNII-6IC8NZ97S2DDTMABrDTABDctabLTABLaurtrimonium bromideN,N,N-Trimethyl-1-dodecanaminiuim bromideN-Lauryl-N,N,N-trimethylammonium bromide
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
PreservativeAnti-static agentSoftener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 24 of 24 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 10 | mg/kg/d | - | dermal | mouse | UnifiedCodex:CIR:beta.noael_studies |
| 6IC8NZ97S2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6IC8NZ97S2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6IC8NZ97S2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6IC8NZ97S2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =10 | mg/kg/d | NOAEL | dermal | mouse | CIR_vision_codex |
| =10 | mg/kg/d | NOAEL | dermal | mouse | CIR_vision_codex |
| =10 | mg/kg/d | NOAEL | dermal | mouse | CIR_vision_codex |
| =10 | mg/kg/d | NOAEL | dermal | mouse | CIR_vision_codex |
| =69 | % | NOAEL | oral | mouse | CIR_vision_codex |
| =69 | % | NOAEL | oral | mouse | CIR_vision_codex |
| =69 | % | NOAEL | oral | mouse | CIR_vision_codex |
| =69 | % | NOAEL | oral | mouse | CIR_vision_codex |
| =100 | mg/kg | NOAEL | oral | rat | CIR_vision_codex |
| =100 | mg/kg | NOAEL | oral | rat | CIR_vision_codex |
| =100 | mg/kg | NOAEL | oral | rat | CIR_vision_codex |
| =100 | mg/kg | NOAEL | oral | rat | CIR_vision_codex |
| =500 | mg/kg/d | NOAEL | oral | rat | CIR_vision_codex |
| =500 | mg/kg/d | NOAEL | oral | rat | CIR_vision_codex |
| =500 | mg/kg/d | NOAEL | oral | rat | CIR_vision_codex |
| =500 | mg/kg/d | NOAEL | oral | rat | CIR_vision_codex |
| 69 | % | developmental toxicity | oral | mouse | UnifiedCodex:CIR:beta.noael_studies |
| 100 | mg/kg | oral toxicity | oral | rat | UnifiedCodex:CIR:beta.noael_studies |
| 500 | mg/kg/d | oral toxicity | oral | rat | UnifiedCodex:CIR:beta.noael_studies |
Showing 24 of 24 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Dodecyltrimethylammonium bromide | 214-290-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL109873
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Frequently Asked Questions
What regulatory lists include Dodecyltrimethylammonium bromide?
Dodecyltrimethylammonium bromide appears on 1 regulatory/inventory list including active_ingredient; Europe; Pesticides. Source: EPA CPDat.
Is Dodecyltrimethylammonium bromide used in cosmetics?
Yes, Dodecyltrimethylammonium bromide is also indexed as a cosmetic ingredient under the name Laurtrimonium Bromide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Dodecyltrimethylammonium bromide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Dodecyltrimethylammonium bromide have different safety status in cosmetics vs industrial chemicals?
Dodecyltrimethylammonium bromide is classified GHS Danger (H301, H302, H315, H317, H319, H335, H400, H410) in the chemicals database but is allowed in EU cosmetics.
Is Dodecyltrimethylammonium bromide used outside industrial chemicals?
Dodecyltrimethylammonium bromide also appears in cosmetics, pharmaceutical databases.