Also known as: 4-06-00-00020, BRN 0906744, Cyclohexanone cyclohexanol mixture, EINECS 203-630-6, Hydralin (+4 more)
CAS 108-93-0
Cyclohexanol (CAS 108-93-0) is a chemical substance with GHS signal word Warning; key hazard signal: H332; H302; H335; H315. Key regulatory status: California Proposition 65, REACH registered, 9 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, CA Prop 65, ILO ICSC, OSHA, EPA TRI.
CAS, identifiers, formula, and alternate names for the matched substance record.
California OEHHA listing status and toxicity category.
| Chemical | Toxicity Type | Cancer | Developmental | Listed |
|---|---|---|---|---|
| - | male | No | No | - |
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Acute Tox. 4 *; Acute Tox. 4 *; STOT SE 3; Skin Irrit. 2 | H332; H302; H335; H315 | GHS07 | Warning |
International Chemical Safety Card hazard and exposure summary.
| Field | Value |
|---|---|
| Short-term Effects | The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system. |
| Long-term Effects | The substance defats the skin, which may cause dryness or cracking. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation and by ingestion. |
Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.
| Agency | Metric | Value | ppm | mg/m3 | Skin |
|---|---|---|---|---|---|
| OSHA | TWA | 50 ppm (200 mg/m³) | 50 | 200 | N |
| NIOSH | TWA | 50 ppm (200 mg/m³) | 50 | 200 | Y |
| ACGIH | TWA | 50 ppm [1979] | 50 | - | Y |
| CAL/OSHA | TWA | 50 ppm (200 mg/m³) | 50 | 200 | Y |
| NIOSH | IDLH | 400 ppm | 400 | - | - |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| artificial_sweat; emissions; Europe; nondetect; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| artificial_saliva; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| Canada; pharmaceutical | DrugBank | DrugBank |
| detected; Other indirect contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| ABmale | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| ABmale | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| ABmale | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| =40.3 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 79.8 | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 8E7S519M3P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8E7S519M3P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8E7S519M3P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8E7S519M3P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1 | unitless | GHS Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 0.31 | %/sec | Intensity | Ocular | - | NTP_ICE_eye_irritation |
| >3.6 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| >3.63 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| =1400 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =1550 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =2060 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =400 | mg/kg bw/day | LOEL | injection | Rat | ToxValDB_ECOTOX |
| - | s | Lag time | Ocular | - | NTP_ICE_eye_irritation |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =614.488 | mg/m3 | NOAEL | inhalation | Rat | ToxValDB_HPVIS |
| 56 | % | Plateau level | Ocular | - | NTP_ICE_eye_irritation |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 24 of 24 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Cyclohexanol | 203-630-6 | ECHA overview → |
TRI hazard and reporting flags for the matched chemical.
| Chemical | Category | Flags |
|---|---|---|
| Cyclohexanol | - | - |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Same-CAS cannabis compliance and lab records where available.
1 cannabis record found in efsa substances.
View full cannabis profile →Cyclohexanol (CAS 108-93-0) is classified under EU CLP Annex VI as Acute Tox. 4 *; Acute Tox. 4 *; STOT SE 3; Skin Irrit. 2 with signal word Warning. Hazard statements: H332; H302; H335; H315. Source: EU CLP Annex VI (ECHA).
Cyclohexanol has 24 NOAEL studies in the database. The lowest reported value is male listing type. Source: California Proposition 65.
Cyclohexanol appears on 9 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, artificial_sweat; emissions; Europe; nondetect; Toys and children's products, artificial_saliva; detected; emissions; Europe; Toys and children's products, and 6 more. Source: EPA CPDat.
Yes, Cyclohexanol is listed under California Proposition 65 for male. Source: California OEHHA Proposition 65.
Occupational exposure limits for Cyclohexanol are set by OSHA, NIOSH, ACGIH. 5 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.
Yes, Cyclohexanol is also indexed as a cosmetic ingredient under the name Cyclohexanol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, California Proposition 65, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, EPA Toxics Release Inventory, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Cyclohexanol also appears in cosmetics, pharmaceutical, cannabis databases.