What is the NOAEL for Methyl hexanoate?
Methyl hexanoate has 8 NOAEL studies in the database. The lowest reported value is 246364VPJS UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Methyl hexanoate
Also known as: BRN 1744683, EINECS 203-425-1, FEMA No. 2708, UNII-246364VPJS, Caproic acid methyl ester (+7 more)
CAS 106-70-7
Methyl hexanoate (CAS 106-70-7) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
Methyl hexanoate
CAS Number
106-70-7
DTXSID
DTXSID0047616
Molecular Formula
C7H14O2
InChI Key
NUKZAGXMHTUAFE-UHFFFAOYSA-N
Monoisotopic Mass
130.09938
Synonyms
BRN 1744683EINECS 203-425-1FEMA No. 2708UNII-246364VPJSCaproic acid methyl esterCaproic acid, methyl esterFEMA 2708Hexanoic acid,methyl esterMethyl N-hexoateMethyl ester of hexanoic acidMethyl hexylateN-Caproic acid methyl ester
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
8 records
Softener and conditionerFragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 246364VPJS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 246364VPJS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 246364VPJS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 246364VPJS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| - | % | Positive reaction | Dermal | Human | NTP_ICE_skin_irritation |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Methyl hexanoate | 203-425-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Methyl hexanoate?
Methyl hexanoate appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is Methyl hexanoate used in cosmetics?
Yes, Methyl hexanoate is also indexed as a cosmetic ingredient under the name Methyl Caproate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Methyl hexanoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Methyl hexanoate used outside industrial chemicals?
Methyl hexanoate also appears in cosmetics, food safety, cannabis databases.