NOAEL Data REACH Registered Cosmetic Ingredient

(2Z)-3,7-dimethylocta-2,6-dienal

CAS 106-26-3

(2Z)-3,7-dimethylocta-2,6-dienal (CAS 106-26-3) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for NERAL →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields

Name

(2Z)-3,7-dimethylocta-2,6-dienal

CAS Number

106-26-3

DTXSID

DTXSID60881216

Molecular Formula

C10H16O

InChI Key

WTEVQBCEXWBHNA-YFHOEESVSA-N

Monoisotopic Mass

152.120115

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 3 records

FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records

List	Keyword	Source
air; detected; emissions; Europe; Vehicle - car interior	Danish Environmental Protection Agency	Danish EPA
detected; Europe; Vehicle - car interior	Danish Environmental Protection Agency	Danish EPA
IFRA Transparency	IFRA	IFRA
Europe	European Commission	Fl@vis

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 31 of 31 studies

Value	Unit	Endpoint	Route	Species	Source
0.3676	%	Concentration, 5% incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
0.2941	%	Concentration, one positive response	Dermal	Human	NTP_ICE_skin_sensitization
=9	mg/m3	DNEL systemic	inhalation	Human	ToxValDB_GESTIS_DNEL
8M466BQL1X	UNII	FDA UNII substance identifier	-	-	openFDA substances
8M466BQL1X	UNII	FDA UNII substance identifier	-	-	openFDA substances
8M466BQL1X	UNII	FDA UNII substance identifier	-	-	openFDA substances
8M466BQL1X	UNII	FDA UNII substance identifier	-	-	openFDA substances
68	%	Incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
3240	ug/cm2	Induction dose per skin area	Dermal	Human	NTP_ICE_skin_sensitization
238.2	ug/cm2	Induction dose per skin area, 5% incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
190.6	ug/cm2	Induction dose per skin area, one positive response	Dermal	Human	NTP_ICE_skin_sensitization
=423.402	mg/m3	LOAEC	inhalation	Rat	ToxValDB_ECHA_IUCLID
=120	mg/kg bw/day	LOAEL	oral	Mouse	ToxValDB_ECHA_IUCLID
=210	mg/kg bw/day	LOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=335	mg/kg bw/day	LOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=345	mg/kg bw/day	LOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=745	mg/kg bw/day	LOAEL	oral	Mouse	ToxValDB_ECHA_IUCLID
=790	mg/kg bw/day	LOAEL	oral	Mouse	ToxValDB_ECHA_IUCLID
=1068	mg/kg bw/day	LOAEL	oral	Mouse	ToxValDB_ECHA_IUCLID
=1140	mg/kg bw/day	LOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=8850	mg/kg bw/day	LOAEL	oral	Mouse	ToxValDB_ECHA_IUCLID
=211.701	mg/m3	NOAEC	inhalation	Rat	ToxValDB_ECHA_IUCLID
=60	mg/kg bw/day	NOAEL	oral	Mouse	ToxValDB_ECHA_IUCLID
=100	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=200	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=534	mg/kg bw/day	NOAEL	oral	Mouse	ToxValDB_ECHA_IUCLID
=570	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=1000	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=4275	mg/kg bw/day	NOAEL	oral	Mouse	ToxValDB_ECHA_IUCLID
=2280	mg/kg bw/day	NOEL	oral	Rat	ToxValDB_ECHA_IUCLID
3	unitless	Relative reliability score	Dermal	Human	NTP_ICE_skin_sensitization

Showing 31 of 31 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	(Z)-3,7-dimethylocta-2,6-dienal	203-379-2	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for (2Z)-3,7-dimethylocta-2,6-dienal?

(2Z)-3,7-dimethylocta-2,6-dienal has 31 NOAEL studies in the database. The lowest reported value is 0.2941 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.

What regulatory lists include (2Z)-3,7-dimethylocta-2,6-dienal?

(2Z)-3,7-dimethylocta-2,6-dienal appears on 4 regulatory/inventory lists including air; detected; emissions; Europe; Vehicle - car interior, detected; Europe; Vehicle - car interior, IFRA Transparency, and 1 more. Source: EPA CPDat.

Is (2Z)-3,7-dimethylocta-2,6-dienal used in cosmetics?

Yes, (2Z)-3,7-dimethylocta-2,6-dienal is also indexed as a cosmetic ingredient under the name NERAL. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for (2Z)-3,7-dimethylocta-2,6-dienal come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is (2Z)-3,7-dimethylocta-2,6-dienal used outside industrial chemicals?

(2Z)-3,7-dimethylocta-2,6-dienal also appears in cosmetics, cannabis databases.